Despite the fact that germline methylome resetting in mammalian embryos might exclude this possibility, some sequences in mouse genome, such as intracisternal A particle (IAP) retrotransposons, are pretty much
With the advent of these first-generation novel therapies, the goal of MM treatment shifted from palliation to symptom control to an increasing focus on achieving much deeper responses and prolonging survival. The earlier introduction of high-dose therapy and ASCT in the 1980s and 1990s also ...
Evolution is fascinating because it attempts to answer one of the most basic human questions: Where did life, and human beings, come from? The theory of evolution proposes that life and humans arose through a natural process. A very large number of people do not believe this, which is somet...
way of quantifying the plausibility of models, which makes it possible to decide which model is the best and how much better that model is than the others. We applied the new technology to the ammonium transport and assimilation network, integrating recent and older data of various accuracies,...
product engineering structures that illustrate where each part or subassembly of a BOM fits within the product. ERP and MRP run many of the supply chain and production processes that go into manufacturing a product; along the way, they collect much of the data that goes into the digital twin...
I also have a smoothie every.single.day and have for the past 4-5 years. I make much simpler smoothies that you. Here are my must haves for a successful smoothie: 1. 1 frozen banana (you peel the banana when it is spotted and freeze it. This is, to me, the KEY ingredient to ma...
Until 2014, Boeke's team had assembled the first yeast chromosome. But it cost more than 60 researchers working on seven years. He invited other U.S. labs to join the project, but they showed little interest. "I did try, but people thought it was impossible, crazy, a waste of money,...
How much of your disease risk is genetic? It's complicated. Recently, CRISPR has been approved to treat two blood disorders, and early-stage trials reveal its potential to treat inherited blindness. Here's everything you need to know about the groundbreaking technology. ...
This chapter covers emerging zoonotic diseases, with a focus on the current understanding of how and where zoonotic pathogens circulate, their pathways to emergence, potential for sustained human-to-human transmission, and gaps in our knowledge. The first cluster of infections among people may be re...
This type of study would require the use of multi-color flow cytometry [16] and also intersects with microbiome [17] datasets, but it can be now accomplished with much higher accuracy due to the rise of single-cell RNA-sequencing (scRNA-seq) and single- cell ATAC (assay for transposase-...