” Becraft explains. “Natural mRNAs last for a few days, maybe less, and they express a single protein. They have no context-dependent actions. That means wherever the mRNA is delivered, it’s only going to express a molecule for a short period ...
Describe how the RNA transcript is modified before it can be used to make proteins. Why is there a need for the primase to make an RNA primer for DNA replication? Why can't double stranded RNA take part in the process of translation?
Describe how the RNA transcript is modified before it can be used to make proteins. Explain what mRNA is and rRNA is. Examine three (3) differences between DNA and RNA then explain two (2) main reasons why DNA is the most favorable molecule for genetic material. ...
The regulatory effect of FGF-2 on the secretion of other growth factors is suggested to occur due to the activation of the MAPK pathway from the interaction between FGF-2 and a dual tyrosine kinase receptor on the membrane, leading to a change in the mRNA expression of VEGF and HGF in ...
mRNA 5′ untranslated regions (UTRs), which serve as the entry point for the ribosome during translation, can adopt elaborate RNA secondary and tertiary structures that may regulate translation initiation in a cap-dependent or cap-independent manner. Complex RNA structures in 5′ UTRs, such as ...
Another important innovation in the design of plasmid DNA backbones is the elimination of antibiotic markers. One example of an alternative technology uses non-coding mRNA to spur RNA/RNA interactions. These interactions mediate selection by inhibiting the translation of the marker SacB mRNA,...
(57) to regulate the efficiency of translation termination and mRNA [summary] The present invention provides a method of promoting the degradation of transcripts / or abnormal. The present invention provides methods for identifying a disease state associated with loss of protein complexes, and methods...
A lncRNA can affect the stability of a mRNA transcript: ‘Part IV and Part V.’ Alternatively, a lncRNA can function as a miRNA sponge which indirectly de-represses the expression of a mRNA that would be targeted by the miRNAs. Lastly, a lncRNA can modulate the translation of a mRNA ...
While, from 60 h to 160 h, the trend is reversed. It is known that mRNA poly(A) tail is shortened along with mRNA translation leading to mRNA degradation [48,49]. The lower GFP mRNA copy number in GFP/NS1 group could be a consequence of GFP mRNA extensive translation (Fig. 3C). ...
How do the proteins of the transcription machinery access DNA that is tightly associated in chromatin? Can you explain the DNA-RNA-PROTEIN concept? Explain the differences between DNA and RNA. Explain how the genetic code allows translation of the information contained in an mRNA into a protein ...