How to live long and prosper: autophagy, mitochondria, and aging. Physiology (Bethesda) 2008 ; 23:248 - 62; http://dx.doi.org/ 10.1152/physiol.00013.2008 ; PMID: 18927201Yen WL, Klionsky DJ. How to live long and
Intermittent fasting is a possible way to induce autophagy. Under normal conditions, when the cell has sufficient nutrients, autophagy degrades damaged components in the cell. When fasting starves the cells, autophagy helps digest some of the cell components, to provide the necessary energy for sur...
Autophagy enables cells to survive when nutrients are scarce by breaking down their components. Studies indicate that autophagy is the primary protein degradation mechanism in muscles under limited amino acid supply [51]. Calpain, a calcium-activated protease, does not directly break down muscle ...
The reprogramming of innate immune cells, mostly through epigenetic modifications, that creates a ‘memory’ of the initial insult and generates long-lasting innate immunity to specific triggers. Very-low-density lipoprotein The primary transporter of endogenous triglycerides from the liver to other tiss...
As the name says, asupplementis here to supplement something that is missing. Ideally, we wouldn’t need any because we’re getting everything from our food. But most of the foods in our supermarkets (around 70%) have been depleted and are now void of nutrients in favor of a long shel...
Autophagy-associated dengue vesicles promote viral transmission avoiding antibody neutralization. Sci Rep. 2016;6:32243. Article CAS PubMed PubMed Central Google Scholar Safadi DE, Lebeau G, Lagrave A, Mélade J, Grondin L, Rosanaly S, et al. Extracellular vesicles are conveyors of the NS1 ...
SGG UCN34Δblp mutant, SGG UCN34 Notch and Notch/APC; C57BL/6J RJ SPF/GF; SPF (short term); Notch and Notch/APC mice were given daily intraperitoneal injection of body weight Tamoxifen (50 μg/g) for 5 days; SPF (long term); Notch and Notch/APC mice were given vancomycin (50 μ...
There are some of them will measure your oxygen all night long. You can do a very crude version of what you might get by working with a dedicated facility. I recommend this all the time to people who say, "Well, I don't really have the time for sleep study. What do I do?" ...
They inspire us to confront fears or insecurities we’ve long avoided. Movies have a unique ability to touch our hearts and minds. They provide an escape from reality, allowing us to explore emotions we may not express in everyday life. Through cinematic experiences, we can find comfort in ...
Thank you for sharing these tips. I have a hard time feeling rested after I wake up no matter how long I sleep. I will definitely try some of these things. Reply Katie February 18, 2019 at 5:55 AM Some great suggests from some great research! Thank you. I no longer drink caffeine ...