Erythropoiesis is a dynamic and tightly regulated process which begins at the stem cell level.[13], [14] Hematopoietic stem cells first generate committed erythroid progenitors which then differentiate into morphologically distinct erythroblasts (EBs) which mature into red cells (Fig. 1). This proces...
Exercise can regenerate stem cells to some degree. No pill can do that yet. Eat more plants, less processed meats. Some nutraceuticals have been studied that might increase healthspan, even lifespan. They include Senolytics, NAD+ precursors and upregulators of Autophagy.Last...
The presence of activated and dysfunctional microglia and reactive astrogliosis would also seem to be an invariant finding in vivo both in AD and MCI [20,21,22]. Other commonly reported abnormalities include compromised autophagy and lysosomal clearance accompanied by elevated activity of both glycogen...
leading to a reduction in overall stability at the joint. A symptom of this is that proper form begins to break down as the lifter starts to “muscle through” the motion, subconsciously trying to shift
Modern genetics is based on the idea that genes are passed on to progeny in a predictable fashion, as first described by 19th-century Austrian botanist Gregor Mendel. He determined that genes exist in pairs, and each one of the two has an equal chance of
or even whole cells that are not functioning correctly and can’t be healed. If you have read much about cancer, this may sound like it’s connected, and it is. Regularly allowing cells to be in a state of autophagy makes them more efficient and keeps them from growing into a malignant...
The researchers begin their review by noting that people who keep their skeletal muscles toned tend to live longer, healthier lives. They also note that prior research has shown thatskeletal muscledecline begins when people age into their 30s—but they also point out that muscles can be rejuvenat...
still isn’t well understood, but it seems to bump the heart into autophagy, which is a condition where the heart muscle cells eat their own cellular garbage for energy, thus avoiding damage.Autophagyis the direct physical benefit of fasting, in this case, imposed on the heart, thus savi...
Aids in cellular cleaning (autophagy), which is important to overall health Sunlight UV rays spur the conversion of cholesterol to vitamin D in our body Brief bouts of sun exposure may actually reduce some types of cancer Blood Loss This one is a bit more controversial, but losing a bit of...
Autophagy as an essential cellular antioxidant pathway in neurodegenerative disease. Redox Biol. 2013, 2, 82–90. [Google Scholar] [CrossRef] [PubMed] Sun, Y.M.; Zhang, H.Y.; Chen, D.Z.; Liu, C.B. Theoretical elucidation on the antioxidant mechanism of curcumin, A DFT study. Org....