SGG UCN34Δblp mutant, SGG UCN34 Notch and Notch/APC; C57BL/6J RJ SPF/GF; SPF (short term); Notch and Notch/APC mice were given daily intraperitoneal injection of body weight Tamoxifen (50 μg/g) for 5 days; SPF (long term); Notch and Notch/APC mice were given vancomycin (50 μ...
Your cells start digesting old proteins through thisautophagy process. We could really nerd out on this stuff, but our bodies were truly built to fast. I love bridging the east and west traditions. But you look at the yin and the yang concept, you have a yang that’s very active and d...
Keep that water bottle within reach. Water is the best choice for staying hydrated. It keeps your body functioning well, especially during long viewing sessions. But why stop there? Add some excitement with infused water—think cucumber and mint or berries and basil. Snacking can also play a ...
Once activated by SARS-CoV-2, this protease helps virus 1) to reduce autophagy, the process physiologically aimed to eliminate external microorganisms from the host cells, 2) to sustain the hyper-inflammatory status and 3) to reduce the host anti-viral immune response [35]. The hypothesis of...
What is the long-term outlook for a fast food diet in terms of longevity and quality of life? What factors contribute to the short life span of an erythrocyte? At what age do the processes of aging begin? Explain the importance of life-long learning and brain stimulation to longevity...
Last month I spent several days reading the (exceptional)Pre-Suasion by Robert Cialdini(THE guru of persuasion). Went slow. Took notes. Applied ideas to a public talk on biohacking the following week. Distilled the core concepts in a long recommendation-review for friends. This book became ...
Among all of the hacks above, intermittent fasting has had the most profound impact on my HRV. When you fast for extended periods, your body goes into preservation mode and starts executing ancient cell maintenance programs, such as autophagy. ...
There are tons offoods that are considered anti-inflammatory, and most often your best bet is to reach for fruits and veggies. Some Anti-Inflammatory Vegetables: Cruciferous vegetables: like broccoli, cauliflower, Brussels sprouts, kale, cabbage, and bok choy ...
While it can be effective for some, it’s not a quick fix—long-term success with any fasting plan depends on consistency and a balanced approach. Eat-Stop-Eat With Eat-Stop-Eat, you fast for 24 hours once or twice a week. It’s a more extreme method that can be effective for fat...
Aside from wanting to reach and maintain ketosis, eliminating or severely limiting carbohydrates has many benefits for most people, and especially for those who want to improve their health or lose weight. Carbohydrates break down quickly in the digestive system to provide the body with a fast and...