a drug administered during cardiovascular surgeries,dialysis, and treatment of ischemic strokes to prevent blood clotting. Protamine, which is alkaline, combines with acidic heparin and forms a complex, reversing the anticoagulant effects of both drugs. ...
The prevalence of heparininduced thrombocytopenia increases with each day of heparin use beyond 5-7 days: it is important to limit treatment duration to the minimum needed clinically. Bioavailability and dose response after SC injection are greatly improved and circulating half-life is prolonged to 3...
Still, its use differs among guidelines, and it should be considered when thrombosis is predominant. Low-molecular-weight heparin (LMWH) should be preferred over unfractionated heparin (UFH) [90]. Thrombotic events are more frequently observed in acute lymphoblastic leukemia (ALL), primarily due to...