Various antibody immobilization strategies, including glutaraldehyde (Glu) cross-linking, 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide/N-hydroxysuccinimide (EDC/NHS) chemistry, direct incubation and cysteamine hydrochloride (CH), have been exploited by different research groups21–26, but it is not...
New antiviral approaches for respiratory syncytial virus and other mononegaviruses: inhibiting the RNA polymerase. Antiviral Res. 134, 63–76 (2016). Article CAS PubMed Google Scholar Falsey, A. R. & Walsh, E. E. Relationship of serum antibody to risk of respiratory syncytial virus infection...
The fact that corona viruses are the largest class of RNA-virus in action, allows them a key evolutionary feature: having a much longer RNA strand they have a greater chance for mutations and plastic adaptability to the environment (living organisms where they reproduce). This is the core ...
The genus Enterovirus (EV) of the family Picornaviridae includes poliovirus, coxsackieviruses, echoviruses, numbered enteroviruses and rhinoviruses. These diverse viruses cause a variety of diseases, including non-specific febrile illness, hand-foot-and-
Over a million years of co-evolution, plants have evolved a multilayered defense mechanism against microbes, of which the cell wall is a vital component. Microbes establish a pathogenic relationship with host plants by avoiding the plant cell wall which requires suitable host recognition tactics ...
Incidents of viral outbreaks have increased at an alarming rate over the past decades. The most recent human coronavirus known as COVID-19 (SARS-CoV-2) has already spread around the world and shown R0 values from 2.2 to 2.68. However, the ratio between mortality and number of infections see...
According to the results of a new laboratory study, human body lice are more efficient at transmittingYersinia pestis,the bacterium that causes plague, than previously thought. This supports the possibility that they may have contributed to past pandemics. David Bland and colleagues at the United St...
The “gut microbiota” is a term referring to the assembly of bacteria, archaea, viruses, and fungi that reside in the gastrointestinal (GI) tract of the host and to which a mutual, mostly beneficial relationship is formed (Bäckhed et al., 2005, Neish, 2009, Qin et al., 2010, Thurs...
Why are viruses not classified by Linnaean taxonomy? What contribution did Carolus Linneaus make to modern taxonomy? What is taxonomy in botany? How is a cladogram used in classification? What is the binomial nomenclature taxonomy for modern people?
Albeit the convincing results in about 30% of advanced stage patients, most patients either do not respond to immunotherapies or have severe side effects, which make a cessation of treatment necessary [14]. Oncolytic viruses have recently been integrated in anti-tumour therapies due to their ...