Tamoxifen (TAM) provides an effective agent for treatment of hormone-dependent breast cancer but resistance uniformly ensues upon continued use. Additional... LM Berstein,HW Zheng,JP Wang,... - Endocrine-related cancer 被引量: 122发表: 2003年 ...
According to the FDA, compared to its brand counterpart, an FDA-approved generic drug: • Is chemically the same • Works just as well in the body • Is as safe and effective • Meets the same standards set by the FDA The main difference between the reference brand drug and the ...
aER testing by IHC is preferred for establishing hormone receptor status and is cost effective when tamoxifen is available. When tamoxifen is available at the basic level, IH testing of ER status should also be provided. 当tamoxifen是可利用的时,测试由IHC的ER为建立激素感受器官状态更喜欢和花费有效...
For post-menopausal women with early stage ER+ breast cancer, aromatase inhibitors are recommended to be part of adjuvant endocrine therapy either as up-front therapy or as a switch strategy following initial tamoxifen therapy. Both approaches are equally effective, and both are superior to ...
aER testing by IHC is preferred for establishing hormone receptor status and is cost effective when tamoxifen is available. When tamoxifen is available at the basic level, IH testing of ER status should also be provided. 当tamoxifen是可利用的时,测试由IHC的ER为建立激素感受器官状态更喜欢和花费有效...
Aromasin is also not given to premenopausal women because it does not stop the ovaries from making estrogen. However, if women are willing to also take medication to suppress ovarian function, as well as effective nonhormonal birth control, then it may be given in certain circumstances. ...
Intermediate metabolizer: Process drugs less efficiently; might not be as effective as normal metabolizers Normal metabolizer: Process drugs efficiently; likely to benefit from treatment with fewer side effects Ultrarapid metabolizer: Process drugs too quickly. Some drugs may not be suitable for these ...
But a blood-testing innovation proved to be effective enough to lead rugby officials in Britain to suspend an athlete for violating the ban on Human Growth Hormone in February of that year. The National Football League is now advocating HGH testing, though the NFL Players Association has voiced...
Relief from period cramps.Research shows that fennel is as effective as conventional medicines at easing discomfort from period cramps. Studies also show that fennel can reduce the production of oxytocin and prostaglandin, two hormones that contribute to painful periods. ...
Overall survival as the outcome for randomized clinical trials with effective subsequent therapies. J Clin Oncol. 2011;29:2439–42. https://doi.org/10.1200/JCO.2011.34.6056. Review. Article PubMed PubMed Central Google Scholar Yeh C, Bates SE. Two decades of research toward the treatment of...