A double-blind study demonstrated that 10mg of melatonin given at 8pm for 6 weeks is an effective treatment for tardive dyskinesia, although the magnitude of the effect was only modest. Other natural substances that have been reported to improve tardive dyskinesia include vitamin E, manganese and ...
After DR, the proportion of patients with endoxifen level <15nM increased from 20% to 50%. HFS did not correlate with any other parameter. DR of tamoxifen from 20mg to 10mg daily resulted in halving of endoxifen levels and subjective improvement of HF. While half the dose-reduced patients ...
Cancer is still the leading cause of death globally. The approval of the therapeutic use of monoclonal antibodies against immune checkpoint molecules, notably those that target the proteins PD-1 and PD-L1, has changed the landscape of cancer treatment. In particular, first-line PD-1/PD-L1 inhi...