2011 Special Issue: How feedback inhibition shapes spike-timing-dependent plasticity and its implications for recent Schizophrenia models Porr B;McCabe Ldi;Prodi P;.How feedback inhibitionshapes spike-timing-dependent plasticity and its implicationsfor recent Schizophrenia models.Neural Networks... B Porr...
InhibitionPCPIt has been shown that plasticity is not a fixed property but, in fact, changes depending on the location of the synapse on the neuron and/or changes of biophysical parameters. Here, we investigate how plasticity is shaped by feedback inhibition in a cortical microcircuit. We use...
How do enzymes work structurally and energetically? How do enzyme inhibitors work, including different types of inhibitors such as competitive, allosteric, and feedback inhibition? What factors in the environment can affect enzyme function? How is the activity of an enzyme is re...
Feedback inhibition control The firing rate of the large-scale neural masses (Eqs. 3 and 4) depends on synaptic input currents (Eqs. 1 and 2), which are, to a large degree, determined by the structural connectome \(C\), that is, large-scale inputs, and associated parameters (\({w}...
The current understanding is that BoNTs potentially inhibit itch at several levels, through the blockade of neurotransmitter and neuropeptide release; the blockade of mast cell degranulation; the downregulation of TRPs; and the inhibition of key players in the neuro-immune system, such as cytokines ...
We're learning more about the craving that fuels self-defeating habits—and how new discoveries can help us kick the habit.
5. Do Bite Inhibition Training Bite inhibition training is training your dog with feedback on how to moderate the pressure they apply when biting, to teach them to have a “soft mouth”. Consistently ending playtime whenever they break the rules will teach them that biting stops the fun. Si...
Commercialization is widely believed to be achievable for metal halide perovskite solar cells with high efficiency and low fabrication cost. However, stability remains a key obstacle for them to compete with established photovoltaic technologies. The pho
Many people promise to exercise more in the new year, but jump-starting your workout routine can be challenging if you've been sitting on the couch for a while. It can seem like a daunting task. Ad Dr. Nathan LeBrasseur, director of the Robert and Arlene Kogod Center on Aging at May...
(e.g., brushing or using interdental cleaning tools), chemical inhibition (e.g., using chlorhexidine or povidone-iodine), and biological interventions (e.g., using probiotics)4. To effectively prevent dental caries, current strategies should aim to suppress the overgrowth of specific cariogenic ...