To help understand how the estrogenic regulation of autophagy affects cell fate, a hypothetical model is pre- sented here. Finally, we discuss some exciting new directions in the field. We hope this might help to better understand the multiple associations between estrogen and autophagy, the ...
To that end I edited the article and removed some of the language I feel does not reflect how I see the world. To be clear I am not in any way going back on my aggressive beliefs or goals. I just realized that I was wrong to think that these goals must be in opposition to the ...
Over the last two decades, the understanding of how dysregulated ion channels and transporters are involved in carcinogenesis and tumor growth and progression, including invasiveness and metastasis, has been increasing exponentially. The present review s
Hormonally, men and women typically experience a decrease in sex hormones such as estrogen, testosterone, and progesterone at around 50 years old, give or take a decade. This shift can lead to the aforementioned decreases inmuscle massand bone density and can also impact sleep, weight gain, an...
Vascular smooth muscle cells (VSMCs) are the most abundant cell in vessels. Earlier experiments have found that VSMCs possess high plasticity. Vascular injury stimulates VSMCs to switch into a dedifferentiated type, also known as synthetic VSMCs, with a
Kessel recently reported the capacity of Hyp to target the ER for photodamage, which provokes a mainly unexplored manner of photokilling that implicates extensive cytoplasmic vacuole formation but does not represent autophagy. This has been called ‘paraptosis’ and seems to be a response to the app...
Your cells start digesting old proteins through thisautophagy process. We could really nerd out on this stuff, but our bodies were truly built to fast. I love bridging the east and west traditions. But you look at the yin and the yang concept, you have a yang that’s very active and ...
Still, by eating less regularly, you promote a process of deep cellular healing called autophagy that does wonders for your health. Intermittent fasting refers to constriction of the daily feeding window, optimally between 12-18 hours of fasting (and 6-12 hours of eating). Ideally, you want ...
How does estrogen work on autophagydoi:10.1080/15548627.2018.1520549Jin XiangXiang LiuJing RenKun ChenHong-lu WangYu-yang MiaoMiao-miao QiTaylor & Francis
The molecular biologists who work in the field of cancer believe that cancer cells can obtain resistance to chemotherapy and enhance their proliferation using autophagy induction [179,180]. Accumulating data has investigated the role of autophagy and its regulation in chemoresistance [181,182]. The ...