Hartter S,Huwel S,Lohmann T,et al.How does the benzamide antipsychotic amisulpride get into the brain?--An in vitro approach comparing amisulpride with clozapine. Neuropsychopharmacology . 2003Hartter S, Huwel S, Lohmann T, Abou El Ela A, Langguth P, Hiemke C, Galla HJ (2003) How does...
have been found to be lower in the cerebrospinal fluid (CSF, or "spinal fluid") and brain of suicide victims. Neurotransmitters send their signals in the brain by binding to receptors, which are proteins on a nerve cell surface. Some types of serotonin receptors are also decreased. Stressleve...
Clozapine (Clozaril, FazaClo, Versacloz) Risperidone (Risperdal) Your bed-wetting may also be due to conditions that affect your body's ability to store and hold urine. For instance,bladder cancerandprostate cancercan cause it. So can diseases of thebrainandspine, such as aseizuredisorder,mu...
Drugs are the factor leading to the highest variability in HRV in the midage patients.72 Alpha-1 blockers, Benzodiazepines, Beta blocker, Bupropion, Clozapine, Cocaine, Fanatrex, Flecainide, Scopolamine, Thioridazine, Tricyclics, etc., globally affects HRV.75 A vagal neuropathy has been observed...
In contrast to the absent effects of classical antipsycho- tics, 1-month treatment with the atypical antipsychotic clozapine does restore P50 suppression in the majority of schizophrenic patients to normal values (see Figure 2), along with superior improvement on (brief) psychiatric rating scales (...
Hallucinogenic drugs, such as LSD, are agonists at serotonin receptor 2A receptor (5-HT2A) and serotonin receptor 2C receptor (5-HT2C) receptors, whereas atypical antipsychotic drugs, such as clozapine and olanzapine, are antagonists. The 5-HT3 receptor, a ligand-gated ion channel, is blocked...
In a light-independent study, the Gq-coupled chemogenetic tool hM3Dq, which reliably induces the depolarization of neurons upon the administration of clozapine N-oxide [CNO] [68], was expressed only in ipRGCs. This allowed for the mimicking of the excitatory effect of light for ipRGCs without...
Studies are conflicting about the usefulness of these different drug classes. It was thought that newer, atypical antipsychotic agents such as clozapine (Clozaril), risperidone (Risperdal), olanzapine (Zyprexa, Zydis), quetiapine (Seroquel), and ziprasidone (Geodon) might have advantages over the ol...
Clozapine treatment is discontinued for a variety of reasons, including non-adherence, intolerance, or lack of efficacy. Patients' experiences of discontinuing the "best" treatment and the impact on perceptions of subsequent antipsychotic treatment are important in developing an understanding of the ...