Imberty A, Mollicone R, Mikros E, Carrupt PA, Perez S, Oriol R: How do antibodies and lectins recognize histo-blood group antigens? A 3D-QSAR study by comparative molecular field analysis (CoMFA). Bioorg Med Chem 1996, 4:1979-1988....
Antibodies, or immunoglobulins, are large Y-shaped glycoproteins that specifically target an invading pathogen and excel at neutralizing bacteria and viruses present in the body’s fluids or extracellular space. They can do this by binding to the surface receptors on the pathogen that may be necessa...
Immunoglobulin G Subclass-Specific Responses against Plasmodium falciparum Merozoite Antigens Are Associated with Control of Parasitemia and Protection fro... Substantial evidence indicates that antibodies to Plasmodium falciparum merozoite antigens play a role in protection from malaria, although the precise...
Through blood transfusions (this is rare in countries where blood is screened for HIV antibodies) HIV also can be transmitted from mother to baby during breastfeeding. The risk of this form of transmission is so small that the World Health Organization now recommends that HIV-positive mothers co...
Also dissolved in plasma are electrolytes, nutrients and vitamins (absorbed from the intestines or produced by the body), hormones, clotting factors, and proteins such as albumin and immunoglobulins (antibodies to fight infection). Plasma distributes the substances it contains as it circulates ...
Monoclonal antibodies help you mount an offense. They attach to cancer cells. Then, like a beacon, they make those cells more visible to your immune system, so it can fight them better. Some monoclonal antibodies can have chemotherapy drugs or radioactive substances attached to them and can he...
There are tests which will consider 20 – 30 autoimmune antibodies, many of which are unrelated to one another. Some of these are tied to known diseases, but many of which are simply speculative. They are not tied to any known human diseases at all. These include: ...
Immune system B cells play a crucial role in the defence of pathogens; when they detect such an intruder, they produce antibodies that help to combat the enemy. They concurrently and continuously improve these molecules to more precisely recognize the pa
Combining the advantages of antibodies in binding a specific target with the capabilities of a therapeutic payload,the majority of ADCs in preclinical and clinical development are for indications in oncology and hematology, where the cytotoxic payloads linked to antibodies are targ...
Monoclonal antibodies are basically antibodies that will attach to the spike protein of the SARS-CoV-2 virus (the virus that causes COVID-19). What it does is once it attaches to that spike protein, the virus cannot attach itself to the cells, thereby limiting the spread of the infection ...