摘要: The present invention relates to a method for the treatment of hyperproliferative diseases such as an antigen associated with hyperproliferative cells, and antibodies that bind to the antigen. Antibodies of the invention are useful in treating, such as neoplasia, hyperproliferative diseases.收藏...
Understand what an antigen is by learning the antigen definition. Also, discover where antigens are found and learn how the immune system responds to antigens. Related to this Question (a) What are antigens? (b) What are Antibodies (Immunoglobulins)?
Imberty A, Mollicone R, Mikros E, Carrupt PA, Perez S, Oriol R: How do antibodies and lectins recognize histo-blood group antigens? A 3D-QSAR study by comparative molecular field analysis (CoMFA). Bioorg Med Chem 1996, 4:1979-1988....
Antibodies are proteins that are responsible for binding to specific parts of pathogens known as epitopes. Once the antibodies bind to these epitopes, they trigger further immune responses and result in the elimination of the pathogenic cells.
Cytokines can help induce the maturation of immature T and B cells. Naïve B cells in the spleen or lymph nodes can be activated in a few different ways, but typically need a more than one step to differentiate into plasma cells that secrete antibodies against a specific antigen and therefo...
An important assumption underlies some theories of antibody diversity; namely, that a single immunoglobulin is complementary to a single antigen or a group of structurally related antigens. These are thought to bind at a single combining site on the immunoglobulin molecule. This review discusses the...
Speculations. How specific are antibodies? An important assumption underlies some theories of antibody diversity; namely, that a single immunoglobulin is complementary to a single antigen or a group of structurally related antigens. These are thought to bind at a single combining......
antigen. When deciding on antibody clonality, the choice depends on what is more critical for the intended application – specificity or sensitivity. While monoclonal secondary antibodies have superior specificity compared to polyclonal antibodies and are preferred for applications requiring highly specific ...
B cells produce antibodies, which bind to antigens and either block viruses and bacteria from entering cells (neutralizing antibodies) or trigger additional immune defenses. The two main types of T cells are CD4 and CD8 cells. CD4, or helper, T cells coordinate the immune response. These are...
Explore All Secondary Antibodies Choosing a Secondary Antibody The choice of appropriate secondary antibody in an application depends on multiple factors, as highlighted below, to ensure highly sensitive and accurate detection of the target antigen. 1. Target specificity –The secondary antibody must be...