Screening & Cell line engineering services: offers tools and services that are designed to improve the outcome of drug discovery and development BioProduction cell lines: offers engineered CHO cell lines that are designed to enable efficient biologics manufacturing Base editing: develops tools and service...
高性价比Horizon CHO-GS cell line Horizon Discovery CHO 细胞系来源于ECACC(欧洲细胞文库) CHO-K1 细胞,应用Horizon Discovery独有的专利技术---重组腺病毒技术, 通过同源重组的方式将GS基因第六外显子(谷氨酰胺合成酶催化活力必须元件)敲除,得到无谷氨酰胺合成酶的CHO-K1细胞系,进一步驯化为悬浮细胞,适应现有商...
Horizon’s proprietary CHOSOURCE™ platform, consisting of a GS knockout CHO K1 cell line combined with a dual promoter expression vector, is now established as an industry standard for host cell line development, faci...
Horizon Discovery的产品线主要可以分为科研cell line、Animal Models、工业生产cell line(CHO)和基因检测标准品。 1.科研cell line:包括HAP1细胞等。这些细胞易于转染,具有快速的倍增时间,并能在单细胞稀释度下持续生长。HAP1细胞是来源于男性慢性粒细胞白血病(CML)细胞株KBM-7的人近单倍体细胞株,大多数常用的细胞...
在生命科学这一充满无限可能的探索领域,HorizonDiscovery以其深厚的科研实力、前瞻性的技术布局以及广泛的国际合作,成为了基因编辑领域的领航者。自2005年成立以来,这家总部位于英国剑桥的科技创新型企业,始终致力于推动生命科学研究的深入发展,为全球科研人员提供高效、安全、可靠的基因编辑工具和服务,为个性化医疗的发展奠...
(GS) knockout CHO K1 cGMP-compliant cell line will complement Rentschler’s existing service to support researchers from early drug development through commercial manufacturing, according to Frank Mathias, CEO of Rentschler. “At Rentschler Biopharma, we consistently strive to offer our clients ...
“We are pleased to enter into this licensing agreement with NGM for this GS knockout CHO K1 cell line to support its broad research and development efforts,” said Dirk Gewert, Business Unit Director, Horizon Discovery. “Horizon aims to empower organizations of all...
(Chinese hamster ovary) line, and will use its proprietary Leap-In®Transposase Technology to offer cell line development services. Horizon has exclusively licensed a vector suite developed by ATUM for the CHO SOURCE platform, to provi...
Exosomes provide a protective and enriched source of miRNA for biomarker profiling compared to intracellular and cell-free blood. J Extracell Vesicles. 2014;26:3. Google Scholar Balaj L, Lessard R, Dai L, Cho YJ, Pomeroy SL, Breakefield XO, et al. Tumour microvesicles contain retrotransposon...
of the “work-horse” CHO cell lines that are used in the manufacture of biological drugs (biologics) such as antibodies. By using genetically modified cells, the production of the biologics can be improved resulting in outcomes which are quicker, cheaper, better or a combination of all three...