A Full-Service Cell Line Development Rely on Our CLD Experts to Generate Your High-Performing Cell Lines As the worldwide demand for protein therapeutics has grown, so has the need for suitable production cell lines. Sartorius can help meet this need with our industry-leading cell line ...
摘要 由于具有复杂的翻译后修饰,悬浮生长良好,对人类易感病毒低感染的优良品质,中国仓鼠卵巢(CHO)细胞已经成了生物制药行业最为广泛的宿主细胞。过去三十年在细胞系的开发和工程化(cell line development and engineering CLD&E)的各个板块中都取得了长足进步,产品产量比过去增加了近100倍。尽管产品的产量始终是细胞系...
Recombinant CHO cell line development (CLD) has been a crucial step for therapeutic protein production platforms; however, this step remains time-consuming and costly. With the emergence of multiomics data sets of CHO cells and genome editing technology such as CRISPR/Cas9, site-specific ...
对于如今需要短时间并快速开发细胞株将是非常有益的。 参考来源:Yong Jae Kim, Sang Kyul Han , Seongtae Yoon , Chan Wha Kim. Rich production media as a platform for CHO cell line development.AMB Express. 2020 May 15;10(1):93. 识别微信二维码,...
Stable Cell Line Development Service for Biopharmaceutical Production As targeted therapies using biopharmaceuticals are becoming more critical, manufacturing processes that speed up their production efficiently, robustly, and cost-effectively gain more importance in order to support patients globally.Chitose ...
对于如今需要短时间并快速开发细胞株将是非常有益的。 参考来源:Yong Jae Kim, SangKyul Han , Seongtae Yoon , Chan Wha Kim. Rich production media as a platform for CHO cell line development.AMB Express. 2020 May 15;10(1):93. 版 权 声 明...
参考资料:CHOMEDIA PLATFORM FACILITATES INTEGRATED CELL LINE DEVELOPMENT AND MEDIA OPTIMIZATION. 注:图文来源于网络 http://weixin.qq.com/r/zRNdRe3EZ7AYrakm90bf (二维码自动识别)本公号所有文章系出于方便读者了解到更多的相关信息,进行传递,共享,科学技术分享之用,不以商业为目的,亦不构成任何投资建议,如本...
[4] Tihanyi B, Nyitray L. Recent advances in CHO cell line development for recombinant protein production. Drug Discov Today Technol. 2020 Dec;38:25-34. doi: 10.1016/j.ddtec.2021.02.003. Epub 2021 Apr 12. PMID: 34895638. [5] Hu J, Han J, Li H, et al. Human Embryonic Kidney 293...
Drug Discovery Today: Technologies,《Recent advances in CHO cell linedevelopmentfor recombinant protein production》,DOI:https://doi.org/10.1016/j.ddtec.2021.02.003 生物治疗在近30年里取得了飞速发展,是目前医药领域中最令人瞩目、最鼓舞人心的焦点,已经成为临...
Landauer K, Woischnigg H, Hepp N et al (2011)Development of a chemically defined CHO medium by engineering based on a feed solution.BMC Proc 5(Suppl 8):P41 CHO MEDIA PLATFORM FACILITATES INTEGRATED CELLLINE DEVELOPMENT AND MEDIA OPTIMIZATION, IrvineScientic Poster in ESACT 2017...