In recent years, MnO2nanostructures have attracted substantial attention as a unique type of TME-responsive theranostic agents23,24. It has been found that MnO2nanostructures would be decomposed by reaction with either H+or glutathione (GSH) existing within the TME, generating Mn2+ions that are ab...
Reactive oxygen species (ROS) are key pathological signals expressed in inflammatory diseases such as cancer, ischemic conditions and atherosclerosis. An ideal drug delivery system should not only be responsive to these signals but also should not elicit an unfavourable host response. This study present...