These findings indicated that miR-4745-5p and miR-6798-5p are serum/glucose starvation-driven miRNAs for hnRNP A1 and validated the λN/boxB system as a simple and useful method for detecting mRNA 3ʹUTR-bound miRNA.Keywords microRNA hnRNP A1 λN/boxB system serum/glucose starvation ...
We identified potential serine arginine rich splicing factor 1 (SRSF1) and heterogeneous nuclear RiboNucleoProtein A1 (hnRNPA1) binding sites at the end of intron 3 and the beginning of exon 4, respectively. RNA immunoprecipitation showed that hnRNPA1, but not SRSF1 could bind to the ...
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发现hnRNPA1通过液-固相转化形成高度稳定且具有显著细胞毒性的不可逆淀粉样纤维聚集体,进一步通过低温冷冻电镜解析致病纤维聚集体的近原子分辨率结构,并阐释其液-固相转化的分子机制。
产品名称: 人异质性胞核核糖核蛋白A1hnRNPA1 elisa试剂盒 产品规格: 48T 96T 有效成分含量: 99% 检测方法: 酶联免疫法 样本: 血清 血浆 细胞上清液 组织等 保质期: 6个月 标记物: HRP 储存条件: 2-8℃,避光防潮保存 用途范围: 试剂盒仅供研究使用,不得用于临床实验或人体实验 是否进口: 否...
A similar effect of hnRNP A1 was demonstrated with mutant hamster adenine phosphoribosyltransferase (aprt) transcripts that are normally constitutively spliced, suggesting that hnRNP A1 may be a general inhibitor of proximal splicing. Intron size also influenced splice site choice in mutant aprt ...
For this purpose the 3′ UTR of CYP2A5 was fused to the coding region of luciferase mRNA. Luciferase recombinants containing either the full length 3′ UTR, or the 3′ UTR lacking a previously described 71 nucleotide (nt) region (the hnRNP A1 primary binding site), were transiently ...
Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection. May play a role in HCV RNA replication.
Alternative Splicing of the Adenylyl Cyclase Stimulatory G-protein Gαs Is Regulated by SF2/ASF and Heterogeneous Nuclear Ribonucleoprotein A1 (hnRNPA1) and Involves the Use of an Unusual TG 3′-Splice Site 来自 国家科技图书文献中心 喜欢 0 阅读量: 34 作者:...