方法 采用 qPCR检测宫颈癌组织和癌旁正常组织中HMMR-AS1的表达量及Hela细胞系中EMT标志物;分析HMMR-AS1表达量与宫颈 癌患者的临床特征,生存期之间的关系;通过CCK-8实验测定高表达HMMR-AS1对宫颈癌细胞增殖速度的影响;通过化 疗药物敏感性实验测定高表达HMMR-AS1后宫颈癌细胞对顺铂的敏感性影响.结果 HMMR-AS1在宫颈...
NONCODING RNA HMMR-AS1TUMOR-GROWTHPROMOTESBackground At present, the role of lncRNA in different kinds of tumors has been widely reported, but its role with hypoxic environment and macrophage polarization is still unclear. Therefore, this study tried to clarify the role of exosomal lncRNA in ...
恶性进展目的探讨长链非编码RNA(long noncoding RNA, lncRNA)HMMR-AS1对肺腺癌(lung adenocarcinoma, LUAD)增殖转移的影响.方法采用实时荧光定量聚合酶链反应技术(RT-qPCR)检测LUAD细胞系中HMMR-AS1及其正义链HMMR的表达水平;通过小干扰RNA敲减HMMR-AS1的水平,并利用RT-qPCR检测转染效率及其对HMMR水平的影响;采用CCK...
CONCLUSIONS: Our data suggested that HMMR-AS1 may be considered a novel prognostic factor in EOC and a specific diagnostic indicator for patients with EOC.Z.-P. ChuJ. DaiL.-G. JiaJ. LiY. ZhangZ.-Y. ZhangP. YanEuropean Review for Medical & Pharmacological Sciences...
Increased expression of long noncoding RNA HMMR-AS1 in epithelial ovarian cancer: an independent prognostic factorZHANG, Z.-Y.CHU, Z.-P.JIA, L.-G.LI, J.ZHANG, Y.YAN, P.DAI, J.European Review for Medical & Pharmacological Sciences
HMMR-AS1The Ryukyu archipelago is located southwest of the Japanese islands, and people originally from this region, the Ryukyu population, have a unique genetic background distinct from that of other populations, including people from mainland Japan. However, few genetic studies have focused on the...
顺铂目的 探讨长链非编码RNA HMMR-AS1在宫颈癌组织中的表达情况及其对顺铂敏感性的影响.方法 采用qPCR检测宫颈癌组织和癌旁正常组织中HMMR-AS1的表达量及Hela细胞系中EMT标志物;分析HMMR-AS1表达量与宫颈癌患者的临床特征,生存期之间的关系;通过CCK-8实验测定高表达HMMR-AS1对宫颈癌细胞增殖速度的影响;通过化疗药物...
Additionally, HMMR-AS1 could target to regulate miRNA-18a, and miRNA-18a could target to regulate ATM. These results imply that L. chinensis seeds inhibit gastric cancer cell proliferation and promote apoptosis through an HMMR-AS1/miRNA-18a/ATM axis; this provides a new line of inquiry for ...
Additionally, HMMR-AS1 could target to regulate miRNA-18a, and miRNA-18a could target to regulate ATM. These results imply that L. chinensis seeds inhibit gastric cancer cell proliferation and promote apoptosis through an HMMR-AS1/miRNA-18a/ATM axis; this provides a new line of inquiry for ...