Coelho博士指出,“当我们敲除褐藻中的性别决定基因MIN时,并没有观察到性别逆转。相反,雄性变成了无性。这是因为它们缺少互补染色体,即雌性 U 染色体。这表明,U 染色体上的雌性诱导因子尚未被发现。”通过这些遗传实验,他们揭示了褐藻中雄性性别决定的复杂机制。 Coelho博士评论说,“将一个HMG-domain基因确定为褐藻的主...
Coelho博士指出,“当我们敲除褐藻中的性别决定基因MIN时,并没有观察到性别逆转。相反,雄性变成了无性。这是因为它们缺少互补染色体,即雌性 U 染色体。这表明,U 染色体上的雌性诱导因子尚未被发现。”通过这些遗传实验,他们揭示了褐藻中雄性性别决定的复杂机制。 Coelho博士评论说,“将一个HMG-domain基因确定为褐藻的主...
Coelho博士指出,“当我们敲除褐藻中的性别决定基因MIN时,并没有观察到性别逆转。相反,雄性变成了无性。这是因为它们缺少互补染色体,即雌性 U 染色体。这表明,U 染色体上的雌性诱导因子尚未被发现。”通过这些遗传实验,他们揭示了褐藻中雄性性别决定的复杂机制。 Coelho博士评论说,“将一个HMG-domain基因确定为褐藻的主...
Coelho博士指出,“当我们敲除褐藻中的性别决定基因MIN时,并没有观察到性别逆转。相反,雄性变成了无性。这是因为它们缺少互补染色体,即雌性 U 染色体。这表明,U 染色体上的雌性诱导因子尚未被发现。”通过这些遗传实验,他们揭示了褐藻中雄性性别决定的复杂机制。 Coelho博士评论说,“将一个HMG-domain基因确定为褐藻的主...
(2008) HMG-box domain stimulation of RAG1/2 cleavage activity is metal ion dependent. BMC Mol Biol 9: pp. 32Kriatchko AN, Bergeron S, Swanson PC. 2008. HMG-box domain stimulation of RAG1/2 cleavage activity is metal ion dependent. BMC Mol. Biol. 9:32...
Interestingly, the inability of a single HMG-box domain to stimulate RAG-mediated RSS cleavage in Mg2+ is overcome by the addition of partner RSS to promote synapsis. Furthermore, we show that mutant forms of HMGB1 which otherwise fail to stimulate RAG-mediated RSS cleavage in Mg2+ can be ...
Erratum to: Deciphering the role of the AT-rich interaction domain and the HMG-box domain of ARID-HMG proteins of Arabidopsis thalianaErratum to: Deciphering the role of the AT-rich interaction domain and the HMG-box domain of ARID-HMG proteins of Arabidopsis thalianadoi:10.1007/s11103-016-053...
Homology model building experiments on HMG-1 box sequences 'threaded' through the 1H-NMR structure of an HMG-1 box from rat indicate that the domain does not have rigid sequence requirements for its formation. Energy calculations indicate that the structure of all HMG-1 box domains is ...
Sox genes encode for transcriptional regulators that are involved in the early embryonic develpoment and in the determination of cell fate. Sox2 is also known as SRY (sex determining region Y)-box2,contain genes that encode for the HMG-box domain that is responsible for DNA binding activity. ...
The HMG (high mobility group) box is a DNA‐binding domain found in several transcription factors, that can in some cases bend DNA. Some members of this protein family recognize a unique DNA sequence, whereas others bind to a common DNA conformation. ...