Chromosomal HMG-box proteins. In: Zlatanova J, Leuba SH, eds. Chromatin structure and dynamics: state-of-the-art. New Comprehensive Biochemistry. Amsterdam: Elsevier Science, 2004:103–134.Travers, A., and Thomas, J. O. (2004) Chromosomal HMG-box proteins. In Chromatin Structure and ...
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Flexing DNA: HMG-box proteins and their partners. The initiation of transcription by RNA polymerase II is controlled by the assembly of the basal transcription machinery, which integrates inputs from trans... ME Bianchi,M Beltrame - 《American Journal of Human Genetics》 被引量: 383发表: 1998...
背景资料:HBP1isamemberoftheHMGfamilyoftranscriptionfactors,whicharecharacterizedbythepresenceofaconservedproteinmotif,thehighmobilitygroup(HMG)1box,thatmediatesDNAbinding.HBP-1bindstothetumorsuppressorproteinsRbandp130andinitiatescellcyclearrest.Terminalcelldifferentiationrequiresthisinitialcellcyclearrestfollowedbythecoo...
Sox genes are a family of genes that encode proteins which are characterized by the presence of a HMG-box related to that of the mammalian sex-determining gene SRY. SRY蛋白含有204个氨基酸,其中1个约79个氨基酸区域即HMG盒(high mobility group box)是SRY基因编码蛋白质的唯一功能区。4...
蛋白别名:High mobility group protein 2-like 1; high-mobility group protein 2-like 1; HMG box domain containing 4; HMG box-containing protein 4; HMG domain-containing protein 4; Protein HMGBCG; Protein THC211630 基因别名:HMG2L1; HMGBCG; HMGXB4; THC211630 ...
Two groups of HMG box proteins are distinguished. Proteins in the first group contain multiple HMG boxes, are non-sequence-specific, and recognize structural features as found in cruciform DNA and cross-over DNA. The abundant chromosomal protein HMG-1 belongs to this subgroup. Proteins in the ...
HMG包含三大家族:HMGB(HMG box proteins),HMGA(AT hook proteins),HMGN(NBD proteins)。其中,HMGA基因作为原癌基因,HMGA蛋白在细胞增生中起到一定的作用。由于HMGA蛋白家族具有改变染色体结构的能力,因此可调节多种目的基因表达,使其通常被认为是结构性转录因子〔2〕。HMGA参与转录调节、胚胎形成、分化、致瘤性转化等...
the HMG-I/Y subfamily and the HMG-14/-17 subfamily. The HMG-1 domain (often referred to as the HMG-1 box) is the functional motif of the largest HMG subfamily, the HMG-1/-2 proteins; the AT hook is the functional motif of the HMG-I/Y group, and the nucleosomal binding domain ...
The HMG (high mobility group) proteins are nonhistone chromosomal proteins that is present in almost all eukaryotic cells, and it functions to stabilize nucleosome formation and acts as a transcription-factor-like protein that regulates the expression of several genes. HMG20A has a role in the in...