Robinson, AP, Caldis, MW, Harp, CT, Goings, GE, Miller, SD (2013) High-mobility group box 1 protein (HMGB1) neutralization ameliorates experimental autoimmune encephalomyelitis. J Autoimmun 43: pp. 32-43High-mo
High-mobility group box 1 protein (HMGB1), which previously was thought to function only as a nuclear factor that enhances transcription, was recently discovered to be a crucial cytokine that mediates the response to infection, injury and inflammation. These observations have led to the emergence ...
高迁移率族蛋白B1(high mobility group box 1 protein, HMGB 1)是巨噬细胞释放出一种核蛋白。HMGB家族有3个成员,即HMGB1、HMGB2和HMGB3,三者在氨基酸序列上有80%的一致性。HMGB1是含量最丰富的HMG蛋白,在典型的哺乳动物细胞内约有106个分子,平均10~15个核小体即可含有1个HMGB1分子。HMGB1广泛分布于淋巴组织、...
Here, we found that pretreatment with high mobility group box-1 protein (HMGB1) in vivo can induce trained immunity in DCs. These trained DCs demonstrated an enhanced ability to present alloantigen, accelerating allograft rejection in a CTLA4-Ig–induced chronic rejection model by upregulating the ...
The aim of this prospective study was therefore to evaluate the diagnostic value of preoperative serum High Mobility Group Box Protein-1 (HMGB-1) levels in patients with Acute Appendicitis (AA) who show normal white blood cell count (WBC) counts. Our study was carried out from October 2010...
High Mobility Group Box Protein 1 (HMGB1)-Partner Molecule Complexes Enhance Cytokine Production by Signaling Through the Partner Molecule Receptor Hulda Sigridur Hreggvidsdóttir,1 Anna M Lundberg,2 Ann-Charlotte Aveberger,3 Lena Klevenvall,3 Ulf Andersson,3 and Helena Erlandsson Harris1 1...
上海玉博生物科技有限公司 主要致力于“HMGB1 (High Mobility Group Box protein 1) 高迁移率族蛋白-1(抗原) yb-0664P”的生产销售。多年的“HMGB1 (High Mobility Group Box protein 1) 高迁移率族蛋白-1(抗原) yb-0664P”生产与销售的经验,与各行业新老用户建立了稳定
Recent evidence has indicated that some pro-inflammatory cytokines and chemokines released by immunocytes are substantially responsible for the progress and consequences of inflammation. High mobility group box 1 (HMGB1) is a nonhistone DNA-binding nuclear protein that plays a crucial role in DNA bin...
High-mobility group box 1 protein (HMGB1), previously known as HMG-1 or amphoterin, is a member of the high mobility group box family of non-histone chromosomal proteins. Human HMGB1 is expressed as a 30 kDa, 215 amino acid (aa) single chain polypeptide containing three domains: two N-...
1.High mobility group box 1 protein(HMGB1)is originally identified as a DNA-binding protein that functions as a structural co-factor. 人高迁移率族蛋白B1(HMGB1)是细胞核内典型的非组蛋白。2) human high-mobility group box-1(HMGB1) 人高迁移率族蛋白B1(HMGB1)...