Allogeneic HLA-matched donor dendritic cells loaded with patient leukemic blasts preferentially induce CD4-positive leukemia-reactive donor lymphocytes. Thomas-Kaskel AK,Portugal TG,Herchenbach D, et al. Acta Haematologica . 2007Thomas-Kaskel AK, Portugal TG, Herchenbach D, Houet LV, Finke HJ (...
RESULTS: Of 153 donor-recipient pairs, 22 (14.4%) were HLA-DPB1 matches, 64 (42.8%) permissive mismatches, and 67 (43.8%) non-permissive mismatches. DPB1 mismatch increased risk of chronic graft-versus-host disease (cGVHD; RR 2.89 [1.19-9.53], P=.016) compared with DPB1-matched ...
To the Editor: Both Dr Verlinsky and colleagues1 and Dr Fost2 argue that in vitro fertilization (IVF) with preimplantation HLA matching poses no risk of creating a donor child with either DBA or acute leukemia. However, the procedure may inadvertently transfer unidentified DBA genes, as cases ...
Effect of haplotype frequency distribution of donor and patient populations on donor search outcome. For details regarding the populations with more diverse and less diverse haplotype frequency distributions see the Methods section. All registries included 2.6 M donors and had the same typing profile com...
(2001), Stem cell transplantation from HLA-matched related donor for Fanconi's anaemia: a retrospective review of the multicentric Italian experience on behalf of Associazione Italiana di Ematologia ed Oncologia Pediatrica (AIEOP)–Gruppo Italiano Trapianto di Midollo Osseo (GITMO). British Journal ...
matched stem cell donors can remain unidentified in donor searches Jürgen Sauter, Ute V. Solloch, Anette S. Giani, Jan A. Hofmann & Alexander H. Schmidt The heterogeneous nature of HLA information in real-life stem cell donor registries may hamper unrelated donor searches....
Thus, how to best select a donor while considering these factors (donor age and sex-mismatch) is unclear. Objective: Examine the impact of donor characteristics [age (younger 35 years), donor-recipient CMV and sex mismatch (F-to-M vs others)], along with patient and HCT-related variables...
Matched sibling donor haematopoietic stem cell transplantation in Fanconi anaemia: an update of the Cincinnati Children’s experience Br J Haematol, 136 (2007), pp. 633-640 CrossrefView in ScopusGoogle Scholar 20 M. Bitan, R. Or, M.Y. Shapira, et al. Fludarabine-based reduced intensity cond...
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Using a cut-off of >1000 MFI for antibody presence, both donor and patient HLA antigens were typed using a Luminex-microbead array platform. Retrospectively, charts were reviewed over 4 years in 20 highly alloimmunized patients...