There is no indication for HLA‐matched platelets in patients with negative antibody screens.Aukje L. KreugerSanquin Research,Leiden,The Netherlands↑Leiden University Medical Center,Leiden,The NetherlandsAnja B.U. MkelburgSanquin Blood Bank,Amsterdam,The Netherlands↑University Medical Center Groningen,...
In the present retrospective, matched cohort analysis, 3 aims were pursued: first, to describe RRTs in patients receiving HLA-matched related HCT after a nonmyeloablative regimen; second, to compare their RRTs and nonrelapse mortality (NRM) to those among similar and concurrent patients who receive...
Platelets C. Precursor red blood cells D. Mature red blood cells E. Lymphocytes Concept: Conceptually, HLA antigens [aka major histocompatibility complexes (MHCs)] function to help our bodies recognize self versus nonself, and to assist in antigen presentation. The major classes of HLA are class...
Conditional on HLA matching, 1hCCIs decreased by 3.70 (95% CI, -5.22 to -2.18) with major ABO mismatches.Matched platelet concentrates yielded maximal 1hCCIs, whereas mismatched transfusions still resulted in adequate increments. There is no indication for HLA-matched platelets in patients with ...
A comparison of volume-reduced versus standard HLA/HPA–matched apheresis platelets in alloimmunized adult patientsdoi:10.1111/j.1537-2995.2011.03364.xBACKGROUND: Our blood bank prepares, on indication or request, a volume-reduced (VR) platelet (PLT) product with greater than 95% reduced plasma ...
loss of a previous graft due to immunological reasons in the first year after transplantation, receipt of an organ donated after cardiac death, donor age <5 or >65 years, current or peak panel reactive antibodies (PRA) >25%, platelets <75,000/mm3, an absolute neutrophil count of <1.500/...
The median time to neutrophil recovery over 500 × 103/mm3 was 24 days (range, 0-35 days) and to last platelet transfusion to keep platelets counts over 50 × 103/mm3 was 24 days (range, 0-61 days). Graft failure was not seen in HLA-matched patients, but 43% of the haploidentical...