http://.abcam/HLA-Class-I-antibody-W632-ab7855.html 1 RelevanceHLACLassIisinvolvedinthepresentationofforeignantigenstotheimmunesystem. CellularlocalizationPlasmamembrane Pleasenote:Allproductsare"FORRESEARCHUSEONLYANDARENOTINTENDEDFORDIAGNOSTICORTHERAPEUTICUSE" ...
Storage: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Background:HLA-C belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-...
Hyperexpression of classical HLA class I (HLA-I) molecules in insulin-containing islets has become a widely accepted hallmark of type 1 diabetes pathology. In comparison, relatively little is known about the expression, function and role of non-classical subtypes of HLA-I. This review focuses on...
Therapeutic Immunoglobulin Intravenous (IVIg), approved to treat a wide range of autoimmune and primary immunodeficiency diseases, contain mixture of polyreactive and polyclonal IgG purified from the pooled plasma of thousands of donors. The aim of this study is to characterize the profiles of a...
Multivalent, multispecific molecules having at least one specificity for a pathogen and at least one specificity for the HLA class II invariant chain (Ii) are administered to induce clearance of the pathogen. In addition to pathogens, clearance of therapeutic or diagnostic agents, autoantibodies, anti...
antibodies to hla class i in ivig rapid publication antibodies to a conserved region of hla class i molecules, capable of modulating cd8 t cell-mediated function, are present in pooled normal immunoglobulin for therapeutic use 来自 万方 喜欢 0 阅读量: 9 作者:...
Cancer stem cells have been proposed to be responsible for tumorigenesis and recurrence in various neoplastic diseases, including multiple myeloma (MM). We have previously reported that MM cells specifically express HLA class I at high levels and that si
英文名称: Anti-MHC class I antigen B 15 总访问: 955 国产/进口: 进口 半年访问: 14 产地/品牌: 进口/国产 产品类别: 抗体 规格: 0.1ml/100μg 最后更新: 2024-11-4 货号: FS1168 CAS 号: 参考报价: 3080 立即询价 电话咨询 [发表评论] [本类其他产品] [本类其他供应商] [收藏] 分享:...
Here, we have described Pr20, a TCR mimic (TCRm) human IgG1 antibody that recognizes the cell-surface ALY peptide/HLA-A2 complex. Pr20 is an immunological tool and potential therapeutic agent. Pr20 bound to PRAME+HLA-A2+ cancers. An afucosylated Fc form (Pr20M) directed antibody-...
A therapeutic target in RA is CD20, and the anti-CD20 antibody Rituxan® (Rituximab), (a chimeric mouse/human monoclonal antibody developed by IDEC Pharmaceuticals) is used in RA treatment. However, Rituxan® contains DR1 and DR4 restricted T cell epitopes, which in the RA population ...