HLA-B27, a valuable genetic marker for spondyloarthritis, offers a means for improved definition of rheumatoid factor negative (seronegative) peripheral arthritis. A group of 109 early-diagnosed patients with seronegative peripheral arthritis, who were under 45 years of age at the onset of disease,...
Twenty of these were HLA-positive and 9 B27 negative. Thirty matched controls were also studied and of these, 15 were negative. Random and directed were measured both by migration through a micropore filter and also by migration under an agar film. The attractant was serum activated either by...
方法采用MLCT法和ELISA法同步检测483例患者的HLA-B27的表达.结果两种方法经配对χ2检验(χ2=80.378,P〈0.01).Kappa值评价(K=0.308),显示两种方法一致程度不够满意.MLCT法敏感度,阳性预测价值和阴性预测价值分别为0.801 1,0.980 3,0.888 2,均优于ELISA法.结论两种方法检测HLA-B27存在差异,ELISA法的敏感度较低,...
ME1 epitope of HLA-B27 confers class I-mediated modulation of gram- negative bacterial invasion J. Immunol, 153 (1994), pp. 833-840 CrossrefView in ScopusGoogle Scholar 40. Barnstable C.J., Bodmer W.F., Brown G., Galfre G., Milstein C., Williams A.F., Ziegler A. Production of ...
(Fig.4cand Supplementary Table1). Moreover, it was observed that 10F04 TCR-T cells only recognized HeLa cells transduced with HLA-DRA/DRB1*09:01 (HeLa-DR0901), but not any other HPV18-negative cancer cell lines, such as Huh7, A549, PANC1, HGC-27 and Lovo (Supplementary Fig.6b, c...
11. To couple (electric circuits) by means of a transformer. v. intr. 1. To be exactly like another; correspond exactly: Do the two socks match? 2. To harmonize with another: My shirt and my tie match. [Middle English macche, from Old English gemæcca, companion, mate; see ma...
01. It is well established that patients carrying these related alleles tolerate abacavir andin vitrofunctional assays are negative. This illustrates the importance of allele-specific sites within the HLA peptide binding groove, where single amino acid changes seen between risk and control alleles can...
In patients suffering from ankylosing spondylitis (AS) HLA-B27 determination by means of the microlymphocytotoxicity test (MLCT) sometimes gives equivocal or false-negative results even though it has been performed with meticulous care. These failures of the test did not arise when the isolated ...
These observations suggest that HLA-G–positive EVT could send a differential signal to uNK cells compared to the signal from maternal HLA-G negative cells in the decidua basalis, but this has not been tested experimentally. HLA-G Since its discovery, HLA-G was thought to be the obvious ...
HLA-B27 is an oddity in that most forms of HLA-B27 (such as the HLA-B27:01 allele) express Bw4, while one particular form (HLA-B27:08) expresses the Bw6 epitope. Since most typing for solid organ transplantation is only for the “antigenic” level, particular alleles can’t usually ...