Structure and Function of the HIV Envelope Glycoprotein as Entry Mediator, Vaccine Immunogen, and Target for Inhibitors. Prabakaran,P. et al. HIV-1:Molecular Biology and Pathogenesis Viral Mechanisms . 2007Prabakaran,P. et al.Structure and Function of the HIV Envelope Glycoprotein as Entry Mediator...
Structure and function of retroviral integrase Article 09 July 2021 The structural basis of herpesvirus entry Article 21 October 2020 Main HIV-1 arose through several independent zoonotic transmissions of simian immunodeficiency viruses during the past century1,2,3. Today, HIV-1, along with its ...
Ten seven-transmembrane-domain G protein-coupled receptors have been identified that are functional HIV-1, HIV-2 and SIV coreceptors. However, the specific structures these receptors have in common that enable them to mediate HIV entry are unknown. Structure–function analyses have revealed that the...
Top of pageIntroduction Conclusion Acknowledgements References Biographies The accessory Nef protein of HIV and SIV is essential for viral pathogenesis, yet it is perplexing in its multitude of molecular functions. In this review we analyse the structure–function relationships of motifs recently proposed...
The aim of this study was to describe the influence of renal damage (RD) and ART on arterial function and structure. Methods: We studied 4 groups of normotensive, normocholesterolemic, euglycemic patients; one of HIV+ on ART with RD (A; n=25; age 50.2±10.4 years; means±SD), one ...
1A–C). The structure and function of the NAc, however, is altered by chronic HIV-1 viral protein exposure [e.g.,11,22,75,76], which may preclude this untoward side effect (i.e., enhanced drug-seeking behavior) in HIV-1 Tg rats treated with SE. Examination of dendritic spine ...
In this review we will focus on the relationship between the structure of the Tat protein and its function as a secreted factor. To this end we will summarize some of the exogenous functions of Tat that have been implicated in HIV-1 pathogenesis and the impact of structural variations and ...
and uninfected cells. In this review we will focus on the relationship between the structure of the Tat protein and its function as a secreted factor. To this end we will summarize some of the exogenous functions of Tat that have been implicated in HIV-1 pathogenesis and the impact of ...
Gasbarrini G, Montalto M: Structure and function of tight junctions. Role in intestinal barrier. Ital J Gastroenterol Hepatol. 1999, 31: 481-8. CAS PubMed Google Scholar Ullrich R, Zeitz M, Heise W, L'age M, Hoffken G, Riecken EO: Small intestinal structure and function in patients ...
(Supplementary Fig.2). Crystals contained four Vpr and two hHR23A-UBA2 molecules in the asymmetric unit, and the structure was solved using the phases from the native Vpr Zn2+anomalous signal, collected at the Zn2+edge (9.65 keV) to 3.0 Å resolution and further extended to 2.2...