[7]JACOBSON K, OGBUAGU O. Integrase inhibitor-based regimens result in more rapid virologic suppression rates among treatment-naïve human immunodeficiency virus-infected patients compared to non-nucleoside and protease inhibitor-based regimens in...
Gilead worked with Japan Tobacco on the HIV integrase inhibitor elvitegravir (Vitekta, 2014). Regrettably, despite being a potent integrase strand transfer inhibitor (INSTI), elvitegravir was extensively metabolized, primarily b...
Gilead worked with Japan Tobacco on the HIV integrase inhibitor elvitegravir (Vitekta, 2014). Regrettably, despite being a potent integrase strand transfer inhibitor (INSTI), elvitegravir was extensively metabolized, primarily by CYP3A4 in both liver and intestine, making a once-daily regimen impossib...
4.HIV drug resistance against strand transfer integrase inhibitors 5.Maraviroc – a CCR5 antagonist for the treatment of HIV-1 infection 6.Enfuvirtide, a New Fusion Inhibitor for Therapy of Human Immunodeficiency Virus Infection 7.Anti-HIV drugs for cancer therapeutics: back to the future? 8.Wikip...
Elvitegravir是一种HIV integrase抑制剂,作用于HIV-1IIIB,HIV-2EHO和HIV-2ROD,IC50分别为0.7nM,2.8nM和1.4nM。 注:本品仅可用于科研实验,严禁用于临床医疗及其他用途! CAS号:697761-98-1 别名:GS-9137;JTK-303;EVG;D06677 纯度:99.78% 分子式:C??H??ClFNO?
4.HIV drug resistance against strand transfer integrase inhibitors 5.Maraviroc – a CCR5 antagonist for the treatment of HIV-1 infection 6.Enfuvirtide, a New Fusion Inhibitor for Therapy of Human Immunodeficiency Virus Infection 7.Anti-HIV drugs for cancer therapeutics: back to the future?
HIV-1 integrase inhibitor((Z)-4-(3-(azidomethyl)phenyl)-2-hydroxy-4-oxobut-2-enoic acid)可用于抗HIV。 HIV-1整合酶抑制剂名称 中文名4-[3-(叠氮基甲基)苯基]-2-羟基-4-氧代-2-丁烯酸 英文名2-Butenoic acid, 4-[3-(azidomethyl)phenyl]-2-hydroxy-4-oxo ...
英文名HIV-1 integrase inhibitor 4 HIV-1整合酶抑制剂4生物活性 描述HIV-1 integrase inhibitor 4 是一种 HIV-1 整合酶链转移 (INST) 抑制剂,其 IC50 值为 3.7 nM。 相关类别 信号通路>>代谢酶/蛋白酶>>艾滋病毒整合酶 信号通路>>抗感染>>HIV ...
中文名称:HIV 编码整合酶 (IN)抑制剂多肽 英文名称:HIV Integrase Protein Inhibitor(1) CAS:172546-75-7 品牌: 上海鸿肽生物 产地: 上海 保存条件: -20℃密封 纯度规格: 98% HPLC 产品类别: 目录肽 货号: 162P12 用途范围: 仅供科研使用 规格: 1mg,10mg,100mg,1000mg,按照您的需求任意包装 是否进口:...
目前,批准用于治疗 AIDS 的抗病毒药物主要有黏附抑制剂(attachment inhibitors,AIs)、逆转录酶抑制剂(reverse transcriptase inhibitors,RTIs)、蛋白酶抑制剂(protease inhibitors,PIs)、整合酶抑制剂(integrase inhibitors,INs)、融合抑制...