We studiedAPOEε2, ε3 and ε4 genotype and 2 clusters of genes: 1) APP-Aβ metabolism genes: 31 genes involved in Aβ production (APP,PSEN1,PSEN2,ADAM9,ADAM10,ADAM17,BACE1,BACE2,NCSTN,PSENEN,APH1B, MEP1B, GPR3), APP stabilization (APLP1,APBA1), APP recycling (SORL1), Aβ depo...
For the present analyses, we selected those SNPs directly genotyped in our GRAS data set with genome-wide significance (Po5 × 10E-8) in the most recent schizophrenia GWAS.2 Pruning based on linkage disequilibrium r2 ⩽ 0.05 as implemented in PLINK23 was carried out. This procedure left ...
With the ability to track the expression of thousands of genes that might be switched on or off in tumours, it's no surprise that micro- arrays are being increasingly used to generate molecular profile maps that identify subgroups of patients who have a high-risk cancer, or who could ...
With the ability to track the expression of thousands of genes that might be switched on or off in tumours, it's no surprise that micro- arrays are being increasingly used to generate molecular profile maps that identify subgroups of patients who have a high-risk cancer, or who could ...