A histidinol-phosphate aminotransferase gene is derived from a Streptomyces luteoverticillatus strain HY61, and the nucleotide sequence of the gene is as shown in SEQ ID NO: 1, and the amino acid sequence of the gene is as shown in SEQ ID NO: 2. The mutant is obtained by means of ...
However, no significant similarity between these proteins and any of the other aminotransferases was detected. A more rigorous analysis, focusing on short sequence segments rather than the total polypeptide chain, revealed that rat tyrosine aminotransferase and Saccharomyces cerevisiae and Escherichia coli ...
Characterization of histidinol phosphate aminotransferase from Escherichia coli. Biochim Biophys Acta. 2003; 1647:321-4. [PubMed: 12686152]Mizuguchi H, Hayashi H, Hirotsu I M K, et al. Charac- terization of histidinol phosphate aminotransferase from Escherichia coli [ J ]. Biochim Biophys Acta,...
In histidine biosynthesis, histidinol-phosphate aminotransferase catalyzes the transfer of the amino group from glutamate to imidazole acetol-phospbate producing 2-oxoglutarate and histidinol phosphate. In some organisms such as the hyperthermophile Thermotoga maritima, specific tyrosine and aromatic amino ...
Evolutionary relationships among aminotransferases - tyrosine aminotransferase, histidinol-phosphate aminotransferase, and aspartate-aminotransferase are homologous proteins. European Journal of Biochemistry 186(1-2): 249-253.MEHTA, K., T. I. HALE, and P. CHRISTEN. 1989. Evolutionary relationships among ...