The HP (Histidine Phosphatase) superfamily, named for a key catalytic His residue, harbors two known groups of protein phosphohistidine phosphatases (PPHPs). The bacterial SixA protein acts as a regulator of His-Asp phosphorelays with two substrates characterized in vitro and/or in vivo. The ...
Extended Data Figure 4 LHPP is a protein histidine phosphatase. a, Diagram of NME1 and NME2 autophosphorylation on His118. The high-energy phosphate is later transferred from the histidine kinase dimer pair to the histidine on the substrate. b, CB1 cell lysate was electrophoresed and transferre...
It is clear that an understanding of protein phosphatase activity is important in delineating the regulation of multistep signaling systems, as they can provide additional regulatory checkpoints in various pathways. This chapter describes the structure and function of E. coli SixA and discusses the ...
The protein histidine phosphatase LHPP is a tumour suppressor Kévin Adam, Sravanth K Hindupur, Yakir Guri … (2018) 0 comments Cited 82 times –based on 0 reviews Review now Bookmark Record: found Abstract: found Article: not found "Inverse Drug Discovery" Strategy To Identify Proteins That...
Protein histidine phosphorylation exists widely in vertebrates, and it plays important roles in signal transduction and other cellular functions. However, knowledge about eukaryotic PHPT (protein histidine phosphatase) is still very limited. To date, only one vertebrate PHPT has been discovered, and tw...
Key words: Histone H1, phosphohistidine phosphatase, phospholysine, phospholysine phosphatase, PHP, PHPT1, protein histidine phosphatase Introduction The discovery of protein phosphorylation on histi- dine (1) was made 52 years ago (2). Most of the work related to phosphohis...
PHPT1 Antibody is a Rabbit Polyclonal antibody against PHPT1. PHPT1 (Phosphohistidine phosphatase 1), also known as 14 kDa phosphohistidine phosphatase, is a 125 amino acid enzyme belonging to the Janus protein family. Existing as a monomer in the cytopl
For this, three key enzymes of the pathway – imidazole glycerol phosphate dehydratase (hisB, Rv1601)24, histidinol dehydrogenase (hisD, Rv1599)18 and histidinol phosphate phosphatase (hisN, Rv3137)25,26, well known for their essentiality were chosen. These enzymes were overexpressed and purified...
cellularcAMPlevel irrespective of the status of receptoradenylate cyclases. This could be the case also for the control of c-di-GMP level. The case of Ser/Thrprotein phosphorylationis even more illuminating. Response regulators with the PPC2-type Ser/Thrprotein phosphatasedomain far outnumber ...
英文名称: Phosphohistidine Phosphatase 1 Human Recombinant 总访问: 268 国产/进口: 进口 半年访问: 26 产地/品牌: prospec 产品类别: 细胞生物学试剂 规格: ENZ-012 最后更新: 2024-12-5 货号: CAS 号: 参考报价: 询价 立即询价 电话咨询