andcerebellum.Inaddition,long-termpotentiation(LTP)is significantlydecreasedinmicelackingtPA.Herewedemon- stratethattPAreceptorLRPisabundantlyexpressedinhip- pocampalneuronsandparticipatesinhippocampalLTP.Perfu- sionofhippocampalsliceswithreceptor-associatedprotein ...
Long-term potentiation (LTP), a form of synaptic plasticity in the hippocampus, is a cellular model for the neural basis of learning and memory, but few studies have investigated the contribution of long-term depression (LTD), a counterpart of LTP. To address the possible relationship between ...
LTP学习与记忆海马诱发电位长时程增强现象(Long- term potentiatio,LTP),常被用来研究与突触可塑性密切相关的学习与记忆过程的分子机制.为了研究微波照射对海马突触可塑性的影响,采用海马齿状回诱发电位的群峰电位幅度(the amplitude of population spikes ,PS amplitude)和群体兴奋性突触后电位的始终上升斜率(the ...
If this is true, epileptogenic lesions should lead to a facilitation of kindling and to an enhancement of long term potentiation (LTP) during the latent period between the occurrence of damage and that of spontaneous epileptic seizures. In the current study, we used the perforant path stimulation...
Postsynaptic mechanisms of hippocampal long-term potentiation (LTP): The involvement of glutamate and non-glutamate receptors as well as second messengers in the late maintenance: Klaus G. Reymann, Stephen N. Davies鈭 , Uwe Frey, Graham L. Collingridge鈭 and H. Matthies, Institute of ...
a是吃饭的时间了 Is time which eats meal [translate] aFinally, we investigated whether O4 treatment influences Aβ42-mediated impairment of hippocampal long-term potentiation (LTP) in rat brain slices 终于,我们调查O4治疗影响是否Aβ42斡旋了hippocampal长期增强(LTP的)损伤在鼠脑子切片 [translate] ...
S. Sex differences in hippocampal long-term potentiation (LTP) and Pavlovian fear conditioning in rats: Positive correlation between LTP and contextual learning. Brain Res. 661, 25–34 (1994). Article CAS PubMed Google Scholar Wiltgen, B. J., Sanders, M. J. & Behne, N. S. Sex ...
Although basal synaptic transmission in the dentate gyrus was normal, there was severe impairment of long-term potentiation (LTP) as a result of reduced activation of NMDA receptors. After suppressing inhibition with picrotoxin, a GABAA receptor antagonist, NMDA receptor-mediated currents were normalize...
mounting evidence points to the involvement of deficits in hippocampal synaptic plasticity. This is supported by the findings that hippocampal long-term potentiation (LTP), a major form of synaptic plasticity widely regarded as a molecular basis for learning and memory, is greatly impaired in differen...
In the present study, three types of synaptic plasticity, long-term potentiation (LTP), long-term depression (LTD) and reversal of LTP (depotentiation, DP), in the field excitatory post-synaptic potential in CA1 hippocampal neurons and learning behavior were examined in β1,4-N-acetylgalacto...