Hippocampal CA1 Pyramidal NeuronsMickus, TimothyJung, HaeyoonSpruston, Nelson
Neurons in Mecp2-deficient mice show lower dendritic spine density in several brain regions. To better understand the role of MeCP2 on excitatory spine synapses, we analyzed dendritic spines of CA1 pyramidal neurons in the hippocampus of M e c p 2 t m 1.1 Jae male mutant mice by either...
We introduce a novel, bias-correction method to estimate the infinitesimal phase-resetting curve (iPRC) and confirm type 1 excitability in hippocampal pyramidal CA1 neurons in vitro by two independent methods. First, PRCs evoked using depolarizing pulses consisted only of advances, consistent with ...
网络锥体神经元 网络释义 1. 锥体神经元 ...石松海结合分子生物学、成像技术和电生理学研究了河马锥体神经元(hippocampal pyramidal neurons)中AMPA-Rs的突触调 … www.cas.cn|基于3个网页
Electrophysiological techniques were used to investigate the effect of stimulating the perforant pathway (PP) on pyramidal neurons in the CA1 region of the hippocampal slice. Stimulation of the PP evoked both field potentials and single unit discharges in the pyramidal cell layer of the CA1 region...
The CA1 region of rat hippocampus contains roughly 320,000–490,000 pyramidal neurons34,35 with about 30–40% of neurons being active in any given environment29,36,37 (Extended Data Fig. 7e). Extrapolating the theoretical curve in Fig. 4g to this number of neurons, we found a close ...
(1995). Pharmacology of postsynaptic metabotropic glutamate receptors in rat hippocampal CA1 pyramidal neurons. Br. J. Pharmacol. 116, 1859-1869.DAVIES C.H., CLARKE V.R., JANE D.E., COLLINGRIDGE G.L. Pharmacology of postsynaptic metabotropic glutamate receptors in rat hippocampal CA1 pyramidal...
In the present study, changes in the electrophysiological properties of hippocampal CA1 pyramidal neurons following amygdala kindling were examined in rat. Methods: Animals were rapidly kindled by stimulation of right amygdala (12 stimulation per day, 1 ms pulse duration at 50Hz). Twenty-four hours...
there turns out to be a very high density of transient A-type potassium ion channels in dendrites of hippocampal CA1 pyramidal neurons. These channels prevent initiation of an action potential in the dendrites, limit the back-propagation of action potentials into the dendrites, and reduce excitator...
As a part of an ongoing investigation to examine gut linked metabolic factors in autism spectrum disorders using a novel rat model, we have observed a possible variation in hippocampal Cornu ammonis 1 (CA1) pyramidal neuron geometry in thin, paraformaldehyde fixed brain sections. However, the ...