HIPEC delivers chemotherapy directly to cancer cells in the abdomen. This allows for higher doses of chemotherapy treatment. Heating the solution may also improve the absorption of chemotherapy drugs by tumors and destroy microscopic cancer cells that remain in the abdomen after surgery. ...
The mice received a continuous intraperitoneal lavage with isotonic saline solution as control or with cisplatin (30 or 60 mg/m) as treatment group for 60 minutes at 37掳C or 42掳C (6 subgroups, each n = 16). Tumor spread was documented by an adapted peritoneal cancer index and MRI (n...
Increased HIPEC-related morbidity compared to the standard surgical approach for the treatment of advanced gastric cancer (OR = 1.67, 95%-CI: 1.13–2.45, p = 0.009) was recently reported, while respiratory complications differed not significantly between both groups (surgery alone vs. ...
Together our data highlight the complexity of HIPEC treatment which goes beyond technical excellence in the operating room but requires a dedicated holistic care of the surgical oncologist. Abbreviations CRS Cytoreductive surgery HIPEC Hyperthermic intraperitoneal chemotherapy PCI Peritoneal cancer index ...
e16070#Background:The prognosis of gastric cancer with peritoneal metastasis (GC-PM) remains dismal. Despite the many studies evaluating hyperthermic intraperitoneal chemotherapy and cytoreductive surgery (HIPEC-CRS) for GC-PM in various treatment settings, its curative role in combination with systemic ...
It also offers a current view of the status of ovarian cancer treatment in our country. Abstract Introduction: Epithelial ovarian cancer (EOC) is primarily confined to the peritoneal cavity. When primary complete surgery is not possible, neoadjuvant chemotherapy (NACT) is provided; however, the ...