This repository contains the EternaBench datasets and accompanying code, which evaluate RNA structure prediction using diverse thermodynamic prediction tasks and high-throughput datasets (Wayment-Steele et al, 2022). Setup Add to python path and point to datasets by adding to .bashrc: ...
We are now seeing the benefit of investments made over the last decade in high-throughput screening (HTS) that is resulting in large structure activity datasets entering public and open databases such as ChEMBL and PubChem. The growth of academic HTS screening centers and the increasing move to...
With the ever-increasing power of supercomputers, materials scientists are able to perform high-throughput density functional theory (DFT) calculations1,2and build up online databases3,4,5,6of important materials properties including structure parameters, thermodynamic and transport properties, and electro...
DNA methylation is a key epigenetic property that drives gene regulatory programs in development and disease. Current single-cell methods that produce high quality methylomes are expensive and low throughput without the aid of extensive automation. We pr
Another recently introduced screening method relies on the enrichment of fluorescence image phenotypes using a fluorescence image-activated cell sorter (ICS),7 which has demonstrated even higher throughput than that of the current GC-based cell sorter. In ICS, a distinct set of image features is qu...
While METABOLIC relies on microbial genomes and metagenomic reads for underpinning its analyses for community-level functional interactions, it can easily integrate transcriptomic datasets to provide an activity-based measure of community networks. The scalable capacity, wide utility, and compatibility for ...
High-throughput serving with various decoding algorithms, including parallel sampling, beam search, and more Tensor parallelism and pipeline parallelism support for distributed inference Streaming outputs OpenAI-compatible API server Support NVIDIA GPUs, AMD CPUs and GPUs, Intel CPUs and GPUs, PowerPC CPU...
The datasets supporting the conclusions of this article and sequences for all primers used in this study are included within the article and its additional file(s). All sequence data generated and used for the current study are available in the DRYAD repository under https://doi.org/10.5061/...
estimate of Δ(E), the energy window was set to −20 to +10 eV around the Fermi level with a largek-mesh and a Lorentzian broadening of 0.25 eV. All calculations were maintained at the same level of numerical accuracy, so that trends over large datasets can be captured correctly...
to quantify regional in vivo RNA hybridization. Corresponding datasets have yielded useful predictions of regions capable of establishing RNA:RNA interactions28. Nonetheless, acquisition of these data is typically limited by low-throughput experiments28,29and reliance on sRNA overexpression that disturbs nat...