Hyphenated HPTLC has been used to analyze several neutral sphingolipids acting as lysosomal storage disease (LSD) biomarkers. Automated multiple development (AMD) provides separation of lipid peaks, which are detected and quantified using fluorescence detection by intensity changes (FDIC) after primuline...
However, due to this effort, it could not be applied to every replicate. Without this, the HILIC-FLD methods reached significantly less molecular resolution (39 species for HILIC-FLD(PROC)-MS). It should be noted that the HILIC-FLD(PROC) method relies on hyphenated electrospray mass ...
If "high resolution" is used alone, where "resolution" is a noun, and "high" is an adjective, it should not be hyphenated. For example, "That image was printed at high resolution."If "high-resolution" is used as a compound adjective, where both words describe another noun, it should ...
Integrating additional separation dimensions with FT-ICR-MS provides additional compositional information, but it adds to the complexity of analyzing large data sets produced by the hyphenated HR-MS method [95]. In order to address the first issue, Riedel and Dittmar [90] have recently proposed a...
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Analogously to hyphenated methods in metabolomics (e.g., LC-MS or GC-MS/MS), the described nuclei preparation procedure allows various combinations of immunolabelling and in situ hybridisation methods in plant cytogenetics. Two of these combinations, immunoFISH and immunoFISH-GISH, have been presen...
A BEH Amide column (2.1 × 100 mm, 1.7 μm) hyphenated with a VanGuard Pre-column (2.1 × 50 mm, 1.7 μm) maintained at 35 °C was used for the UHP-HILIC separation. The same binary mobile phase at the same flow rate as those in RP separation was employed, but followed a ...
Hyphenated high-resolution mass spectrometry—the “all-in-one” device in analytical toxicology? Hans H. Maurer Analytical and Bioanalytical Chemistry (2021) Inter-laboratory reproducibility of an untargeted metabolomics GC–MS assay for analysis of human plasma Yanping Lin Gary W. Caldwell John ...
Aqueous environmental sample analysis is commonly done with mass spectrometry (MS) coupled with gas or liquid chromatographic separation, commonly employing high resolution or tandem MS analysis respectively referred to as GC-MS and LC-MC. Such hyphenated MS techniques are well regarded for their perfo...
Nowadays, researchers commonly use advanced analytical methods, such as gas chromatography hyphenated to mass spectrometry (GC–MS), for the high-throughput identification of compounds [1], [2], [3], [4], [5], [6]. Compared with liquid chromatography–mass spectrometry, GC–MS is more ...