PSA分化的前列腺细胞合成等的治疗和血液中的PSA水平大大受损,前雄激素depriva的不同反映了肿瘤的负担。当疾病成为第一或第二线雄激素剥夺难治,患者可进入化疗或实验各种代理协议(例如,泰索帝,赛诺菲 - 安万特公司,布里奇沃特,NJ)。血液中的PSA水平的评估,选择最佳的治%E ...
In all 3 arms, patients were treated for a finite duration of 52 weeks in the absence of PSA progression or unacceptable toxicity. Following treatment completion, patients were followed with mostly lab assessment until PSA progression, at which point, treatment was per investigator discretion.” Bre...
Clinical Features: Gleason Score, PSA, and DRE. Not all high-risk prostate cancers are defined by a single parameter, but Gleason sc...Kibel A S,Nelson J B.Adjuvant and salvage treatment options for patients with high-risk prostate cancer treated with radical prostatectomy[J].Prostate Cancer ...
136 Phase II prospective study of the use of conformal high dose rate brachytherapy alone for the treatment of favorable stage prostate cancer patients The aim of this study is to analyze, during the prostate-specific antigen (PSA) era, the long-term outcome of patients treated with conformal ...
As inhibition of the AR pathway is the mainstay of systemic PC treatment and AR-V7 is a well described resistance marker in up to 25% of CRPC patients, assessing patients’ AR status over the course of the treatment is highly relevant [80]. PSA is an AR-regulated gene, meaning that ...
Objective: This study compared survival of prostate cancer patients with low prostate specific antigen level (PSA ≤ 10 ng/ml) and high-grades of Gleason score (GS) of 8–10 with different treatment options (i.e., radical prostatectomy [RP], external beam radiotherapy [EBRT...
After discussion of treatment options, 109 patients elected HDR Implant + IMRT and 312 patients underwent HDR monotherapy. No patient received Hormonal Blockade. Median Gleason Score was 7 (range: 4 to 10). Median PSA was 9.8 (0.60 to 39.8). IMRT treatment volume included the prostate + ...
Prostate-specific antigen (PSA) screening, and changes in the diagnostic pathway of prostate cancer, has resulted in proportionally more men being diagnosed with early stage prostate cancer still confined to the prostate. Patients are faced with an overwhelming choice of treatment options to treat ...
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Most of the reason for the 2012 USPSTF recommendation against PSA testing was owing to the detection and treatment of LG PCA, a tumor that is often indolent. With the PSA screening pendulum swinging away from testing, there is a risk that successes in reducing prostate cancer mortality will ...