High PSA levels may show body is fighting cancer.Outlines the results of a study on the treatment of prostate cancer. Significance of the prostate specific antigen; Ability of the antigen to reduce metastases; Experiment on in vitro cells.Josefson...
Acute myocardial infarction without cardiogenic shock does not affect serum prostate specific antigen levels: A case control study The prostate-specific antigen (PSA) serum level is of utmost diagnostic importance as probability of prostate cancer (PCa) increases with increasing serum ... ztekin,C....
B, Decision curve analysis plots illustrating the net reduction in biopsies performed per 100 patients without missing a single diagnosis of cancer of grade group 2 or greater based on prebiopsy testing with PSA alone, the Prostate Cancer Prevention Trial risk calculator, PHI, the derived multiplex...
In both cases, plasma total PSA and several simultaneously measured percent free PSA values were available from time prior to diagnosis of prostate cancer (Fig. 7b, d). In both GP5 and GP12, no significant difference in Gleason pattern or stromal appearance was identified histologically on visual...
Cancer immunotherapies such as bispecific T-cell engagers have seen limited adoption in prostate cancer (PC), possibly due to differing levels of cancer receptor expression and effector T-cell infiltration between patients and inherent defects in T-cell engager design. Methods CD8+ T-cell infiltration...
criteria as it would inflate the event rate. We also conducted univariate and multivariate analyses to associate the SFI-induced MYC signature with clinical outcome after adjusting for other clinicopathologic variables including pre-operative prostate-specific antigen (PSA) levels, seminal vesicle invasion...
In this study, the urine exosome gene expression assay was associated with improved identification of patients with higher-grade prostate cancer among men with elevated PSA levels and could reduce the total number of unnecessary biopsies. Introduction Prostate cancer (PCA) is the most common solid ...
Objectives: To determine the incidence and magnitude of the rapid increase in the serum PSA (riPSA) level after high-intensity focused ultrasound (HIFU) therapy for prostate cancer, and its correlation with clinical factors. Methods: A total of 176 patients with localized prostate cancer underwent...
The reduction in PSA levels with enzalutamide treatment was a strong predictor of eventual survival rates, the analysis showed. Median metastasis-free survival—reflecting how long the men survived without cancer spread—was 37 months in patients with a PSA decline of 90% or greater, compared to ...
Can the number of cores with high-grade prostate intraepithelial neoplasia predict cancer in men who undergo repeat biopsy? To evaluate whether the presence of, or the number of cores containing, high-grade prostatic intraepithelial neoplasia (PIN) found in men who underwent ini... Y Naya,AG Ay...