High Levels of the PSA (Prostate Specific Antigen) In Patients with Benign Prostatic Hyperplasia and Prostate CancerRishu BansaliMedPub
New research shows that prostate specific antigen (PSA), a commonly used serum marker of prostate cancer, inhibits the formation of new blood vessels and consequently slows the progression of the disease (Journal of the National Cancer Institute 1999;91:1635-40).The finding may explain the ...
"We knew going into this research that inflammation in the prostate is very common in men who have biopsies because of the higher PSA levels and other indicators of prostate cancer," said De Marzo, who is a professor of pathology at Johns Hopkins' School of Medicine and associate director of...
Prostate cancer (PrCa) genomic heterogeneity causes resistance to therapies such as androgen deprivation. Such heterogeneity can be deciphered in the context of evolutionary principles, but current clinical trials do not include evolution as an essential
Baseline assessments indicated higher PSA levels and a greater number of bone metastatic lesions among patients experiencing moderate to severe baseline pain compared to those with mild or no pain in both the REZ-ADT and BIC-ADT groups (Supplementary Table 3). Moreover, no obvious correlations we...
Objectives: To determine the incidence and magnitude of the rapid increase in the serum PSA (riPSA) level after high-intensity focused ultrasound (HIFU) therapy for prostate cancer, and its correlation with clinical factors. Methods: A total of 176 patients with localized prostate cancer underwent...
1 In 2012, the US Preventive Services Task Force recommended against routine prostate-specific antigen (PSA) screening owing to risk of overdiagnosis of clinically insignificant prostate cancer. Consequently, there has been a decrease in indolent, localized disease, but a concordant increase of ...
Prostate cancer diagnosis among men with isolated high-grade intraepithelial neoplasia enrolled onto a 3-year prospective phase III clinical trial of oral ... Purpose;Prostate cancer (PCa) prevention remains an appealing strategy for the reduction of overtreatment and secondary adverse effects. We evalu...
In an autopsy study in which women died from causes other than breast cancer, DCIS was identified in about 30% of women between the ages of 40 and 54 years [155]. As one in eight women (12.4%) develops breast cancer during her lifetime in the U.S. [156], this common occurrence ...
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