The mean Au ion intensity in a cell population of interest measured by mass cytometry is termed the ‘mean dual counts’. This value is proportional to the number of Au atoms per cell—and it is the product of the integral over time of detector intensity multiplied by the dual count coeffi...
C. GMP-140 binding to neutrophils is inhibited by sulfated glycans. Journal of Biological Chemistry 266, 5371–5374 (1991). Article CAS Google Scholar Shattil, S. J., Cunningham, M. & Hoxie, J. A. Detection of activated platelets in whole blood using activation-dependent monoclonal ...
Membranous substances were mainly composed of acidophilic stratified structures and inflammatory cells, such as neutrophils and lymphocytes. The acidophilic stratified elements were squamous epithelium-derived keratinocytes (Fig. 6A–F). The effects of MA-T on these membranes are shown in Fig. 6G–L....
It is most well-known as part of the S100A8/A9 complex (calprotectin), which is canonically expressed and secreted by neutrophils, monocytes, and macrophages (Gebhardt et al., 2006). S100A8/A9 is also upregulated in a number of inflammatory disorders such as psoriasis and cystic fibrosis (...
Intracellular oxidative activation in synovial fluid neutrophils from patients with rheumatoid arthritis but not from other arthritis patients. J Rheumatol. 2007;34(11):2162–70. PubMed CAS Google Scholar Khandpur R, et al. NETs are a source of citrullinated autoantigens and stimulate inflammatory...
The median time for neutrophils to reach a level of 0.5 × 109/L for 3 consecutive days was 12 days (range, 10-21 days) in the WM-UDT group, 12 days (range, 9-22 days) in the PM-UDT group, and 11 days (range, 10-17 days) in the FMT group. The median time for the ...
Gilead Sciences to Release Fourth Quarter & Full Year 2024 Financial Results on Tuesday, February 11, 2025 January 28, 2025 Gilead and LEO Pharma Enter Into Strategic Partnership to Accelerate Development of Oral STAT6 Program With Potential in Multiple Inflam...
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Fig. 3: Observing 3D migration of neutrophils in the mouse brain in vivo. a, Low-SNR images of neutrophil migration without denoising. b, Images denoised with DeepCAD-RT. c, Synchronized high-SNR images with tenfold fluorescence photons. Blue arrowheads point to the elongated tail of a migr...
(b) Absolute cell count in binned regions of increasing normalized bound-peptide concentration of formylated (F) or non-formylated (NF) FITC-labeled NLFNTK. n = 3 replicates. Error bars represent SD. (c and d) Location of neutrophils on a formylated (c) or non-formylated (d) ...