Publication » REGRESSION OF CORONARY ATHEROSCLEROSIS IN DIABETIC PATIENTS WITH HIGH INTESITY STATIN REGIMENS: INSIGHTS FROM SATURN.doi:10.1016/S0735-1097(13)61129-8Stegman, BrianCho, LeslieNissen, StevenShao, MingyuanBallantyne, ChristieBarter, Phillip...
Effect of Very High-Intensity Statin Therapy on Regression of Coronary Atherosclerosis: The ASTEROID Trial Prior intravascular ultrasound (IVUS) trials have demonstrated slowing or halting of atherosclerosis progression with statin therapy but have not shown con... M Clearfield - 《Current Atherosclerosis...
1-4 Likewise, high-intensity statin regimens (ie, atorvastatin calcium, ≥40 mg/d, or rosuvastatin, ≥20 mg/d) are recommended as foundational therapy. Whether more intensive lowering of LDL-C levels would benefit patients who already have an LDL-C level of less than 70 mg/dL or patients...
Effect of very high-intensity statin therapy on regression of coronary atherosclerosis: the ASTEROID trial. JAMA. 2006;295(13):1556-1565. doi:10.1001/jama.295.13.jpc60002ArticlePubMedGoogle ScholarCrossref 12. Kini AS, Baber U, Kovacic JC, et al. Changes in plaque lipid ...
Subsequently, some studies hypothesized that using higher potency statins would show a greater reduction in cardiovascular events compared to less intensive regimens. Also, several trials have studied whether the use of high intensity statins impacts the progression of atherosclerosis. In this review, ...
CYP3A4*1B and CYP3A5*3 SNPs significantly impact the response of Egyptian candidates to high-intensity statin therapy to atorvastatin Mohammed G. Maslub, Nur Aizati Athirah Daud, Mahasen A. Radwan, Abubakar Sha’aban & Arafa G. Ibrahim European Journal of Medical Research volume 29,...
High-intensity statin therapy (atorvastatin 40–80 mg/day or rosuvastatin 20–40 mg/day) generally reduces LDL-C levels by ≥50% while moderate-intensity statin therapy reduces LDL-by ≥30% to <50%. However, high-intensity statin therapy may be insufficient to achieve LDL-C targets when ...
For statin-treated patients, the intensity of statin therapy was categorized as low intensity (simvastatin 10 mg, pravastatin 10–20 mg, or fluvastatin 20–40 mg), moderate intensity (atorvastatin 10–20 mg, rosuvastatin 5–10 mg, simvastatin 20–80 mg, pravastatin 40 mg, or fluvastatin 80 ...
High-intensity statin therapy (atorvastatin 40–80 mg/day or rosuvastatin 20–40 mg/day) generally reduces LDL-C levels by ≥50% while moderate-intensity statin therapy reduces LDL-by ≥30% to <50%. However, high-intensity statin therapy may be insufficient to achieve LDL-C targets when ...
Selection of Regimens The study sought to determine the effects of high-intensity lipid lowering on coronary disease progression. Accordingly, we selected a regimen, rosuvastatin, 40 mg/d, that had previously demonstrated the largest reduction in LDL-C of any available statin therapy at the time ...