A large national study has confirmed the value of high-intensity statin treatments for people with cardiovascular disease, according to researchers at the Stanford University School of Medicine. Over the duration of a year, the researchers found that patients taking high-intensity statins had an incre...
Most patients with ASCVD are candidates for high-intensity statins, with a goal for low-density lipoprotein cholesterol reduction of 50% or greater. A subgroup of patients with ASCVD are at very high risk and can benefit by the addition of nonstatin drugs (ezetimibe with or without bile acid...
Cardiovasc Drugs Ther. 2016;30(3):323-331.PubMedGoogle ScholarCrossref 6. Rosenson RS, Kent ST, Brown TM, et al. Underutilization of high-intensity statin therapy after hospitalization for coronary heart disease. J Am Coll Cardiol. 2015;65(3):270-277.PubMedGoogle ScholarCrossref 7. Lin...
CYP3A4*1B and CYP3A5*3 SNPs significantly impact the response of Egyptian candidates to high-intensity statin therapy to atorvastatin Mohammed G. Maslub, Nur Aizati Athirah Daud, Mahasen A. Radwan, Abubakar Sha’aban & Arafa G. Ibrahim European Journal of Medical Research volume 29,...
Treat-to-Target or High-Intensity Statin in Patients With Coronary Artery Disease View LargeDownload Figure 1. Recruitment, Randomization, and Follow-up in a Trial of Treat-to-Target Strategy or High-Intensity Statin Therapy for Coronary Artery Disease View LargeDownload aData regarding screening...
After multivariable adjustment, the risk ratio (RR) for titrating to a high-intensity statin comparing patients with versus without DM was 1.01 (95% CI 0.96, 1.06). Among patients whose first statin fill post-AMI was for a low/moderate-intensity dosage, 7.5% of those with DM titrated to ...
(73%). All the patients were candidates for high-intensity statin therapy. The participants were either predisposed to or already had atherosclerotic cardiovascular disease (ASCVD). Approximately two-thirds (62%) of the subjects were on low-dose aspirin as a prophylactic therapy for CVD events. ...
High-intensity statin is recommended for patients undergoing percutaneous coronary intervention (PCI), and ezetimibe is recommended to be added in patients not achieving low-density lipoprotein cholesterol (LDL-C) targets. Moderate-intensity statin plus ezetimibe can reduce LDL-C levels similar to high...
Background: There is uncertainty regarding the impact of high-intensity statins on postoperative outcomes in patients undergoing surgical myocardial revascularization. This study was conducted to evaluate the impact of high-intensity statin treatment on the occurrence rate of new-onset postoperative atrial ...
Although epicardial adipose tissue thickness at systole can be a useful marker for predicting NOD during high‑intensity statin therapy in a previous study, there are inconsistent findings with the pitvastatin [22]. Mechanisms of pitavastatin Previous studies have suggested several mechanisms of the ...