The first real break in the radiocarbon sequence occurs between the end of Phase 4 and the start of Phase 3, which is marked by the construction and use of Structure 2. The hiatus between the end of Phase 4 and the start of Phase 3 is at minimum 820 years, at maximum 1100 years. T...
yet the evolutionary pathways for resistance development during exposure to low amounts of antibiotics remain poorly defined. Here we show thatSalmonella entericaexposed to sub-MIC levels of streptomycin evolved high-level resistance via novel mechanisms that are different...
We solve this problem with the recently-introduced Multi-Objective Real-Valued Gene- pool Optimal Mixing Evolutionary Algorithm (MO-RV-GOMEA), which is a promising MOEA that is able to e ectively exploit de- pendencies between problem variables to tackle complicated prob- lems in the continuous...
This approach optimizes two minimization objective functions simultaneously by using a proposed multi-objective evolutionary approach. To reduce the difficulty in identifying the subspace of each cluster, the cluster memberships of the objects, and the number of clusters, a two-step method is suggested...
TEs specific to African cichlid species have been previously sequenced and used as molecular markers to study evolutionary history and phylogenetics of African cichlids [40, 41]. Some of these African cichlid specific or “AFC” LINEs and SINEs had been previously assembled and annotated in the Ore...
Surrogate-assisted evolutionary computation have received much more attention in the field of optimization because of its ability to reduce effectively the CPU cost. However, as the dimension of the search space increases, the number of samples required to construct the global accurate surrogate model...
The AMR gene group classification used was neither based on the gene variant-mediated resistance phenotype nor order of discovery, but on gene sequence identity and evolutionary relationship. Therefore, the primers and probe design for each group in this study could potentially target many more AMR...
analyses were suggestive that methylation at the fCpG sites was unlikely to be under strict regulation or evolutionary selection in the colon. Methylation status of fCpGs is conserved along the crypt Previous research has found that the methylation profile of the whole crypt is typically ...
TAD evolutionary and functional characterization reveals diversity in mammalian TAD boundary properties and function Article Open access 07 December 2023 Introduction How the DNA packs into the nucleus and coordinates functional activities is a long-standing question in biology. Recent studies have shown ...
Entangling gates with error rates reaching the threshold for quantum error correction have been reported for CZ gates using adiabatic longitudinal control based on the interaction between the |11〉 and |20〉 states. Here, we design and implement nonadiab