Reports on a finding which suggests that estrogen may play a role in susceptibility to lung cancer. Susceptability of women to the carcinogenic effects of tobacco smoke; Effect of estrogen on cells; Idea that it may take years for the carcinogenic effect of estrogen to result in diagnosable ...
The Centers for Disease Control and Prevention has an analogy about locks and keys to help understand cancer treatment. There are three kinds of locks, or receptors — one is for estrogen (ER), one is for progesterone (PR) and the third is a protein called human epidermal growth factor (H...
Estrogen is an important naturally-occurring hormone. It’s key to women’s sexual and reproductive development. It may support heart-healthy and anti-cancer effects for women and men. Estrogen levels are higher in women, but the evidence is that good levels are also important for men’s heal...
You may also experience low estrogen if you have been given certain drugs. For example, some types of breast cancer treatment involve blocking estrogen production. And your levels may be low immediately after childbirth and during breastfeeding. Why are female athletes and athletes AFAB at risk fo...
These may include obesity, aging, certain medications, and an imbalance of sex hormones. In some cases, the cause is not known or cannot be determined. In addition, certain medical conditions such as liver or kidney failure, testicular cancer, and tumors can cause high estrogen levels in men...
Plasticity delineates cancer subtypes with more or less favourable outcomes. In breast cancer, the subtype triple-negative lacks expression of major differentiation markers, e.g., estrogen receptor α (ERα), and its high cellular plasticity results in g
Modifiable risk factors (alcohol, smoking, obesity, hormone use, and physical activity) affect a woman’s breast cancer (BC) risk. Whether these factors affect BC risk in women with inherited risk (family history, BRCA1/2 mutations, or familial cancer sy
Lonning PE, Taylor PD, Anker G, Iddon J, Wie L, Jorgensen LM, Mella O, and Howell A (2001) High-dose estrogen treatment in postmenopausal breast cancer patients heavily exposed to endocrine therapy. Breast Cancer Res Treat 67: 111-116....
There is a strong association between obesity and colorectal cancer (CRC), especially in men, whereas estrogen protects against both the metabolic syndrome and CRC. Colon is the first organ to respond to high-fat diet (HFD), and estrogen receptor beta (ERβ) can attenuate CRC development. How...
An hitherto undefined androgen binding macromolecule(s), with high-capacity binding for natural and synthetic androgens, but not for estrogen and progesterone, seems to be present in these ovarian cancer tissues. The functionality of these androgen binding macromolecules in ovarian cancer is yet to ...