As a result, gadolinium-based imaging must be avoided in patients with an eGFR < 30 mL/min/1.73 m2. Angiography Following the development of the high-resolution and scanning techniques, CT and MRI have replaced conventional angiography for the analysis of renal vascularization in patients with ...
Male sex, increasing age and systolic blood pressure were independent determinants of both hsTnT and hsTnI. Despite normal renal function (eGFR≥60 mL/min/1.73 m2) in all individuals, a lower eGFR was independently associated with higher hsTnT concentrations, but not with hsTnI (Table 3)...
EGFR epidermal growth factor receptor EGR1 early growth response 1 EGR2 early growth response 2 EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 EIF5AL1 eukaryotic translation initiation factor 5A-like 1 ELK1 ELK1, ETS transcription factor ELOB elongin B ENG Endoglin ENO1 enolase...
Mechanistically, miR-30b-5p suppresses the progression and metastasis of PTC by targeting GALNT7 and subsequently inhibiting the EGFR/PI3K/AKT pathway [128] (Fig. 4). PI3K/AKT is also an important metastasis-related signalling pathway in ATC and PDTC, and PIK3CA mutation contributes to the ...
(C) adjusted for age, sex, race and ethnicity, body mass index, hypertension, diabetes, smoking, triglycerides, low-density lipoprotein (LDL) cholesterol, stroke history, heart attack history, estimated glomerular filtration rate (eGFR), and frequent alcohol use (defined as alcohol consumption ≥3...
In the stone group, the higher proportion of males may lead to lower average calculated eGFR values, particularly when gender has not been appropriately adjusted for. Future research should further explore how gender affects the assessment of renal function in stone patients and consider incorporating...
Individuals with increased UACR showed higher levels of ALT, AST, γ-GGT, blood glucose levels, blood pressure levels, pulse, BMI, HOMA-IR, and Cr and a higher prevalence of CVD events, but lower levels of eGFR. The prevalence of diabetes and hypertension were also notably different between...
Additionally, we used NHANES blood samples data from a single blood extraction. Sequential testing could potentially be more indicative of true physiological states, given the lifespan of blood cells. Thirdly, the database has its own internal limitations, such as using self-reported questionnaire ...
Baseline values of EGFR, GHR, NTRK3, SOD2, KLRF1, THBS2, TIMP1, IGFBP2, C9, APOB, and LRP1B mediated the association between baseline RDW and all-cause mortality. Changes in IGFBP2 and C7 over 9 years mediated the association between changes in RDW and 6-year all-cause mortality....
To invade these cells, gonococci interact with heparin sulphate proteoglycan (HSPG) receptor leading to activation of epidermal growth factor receptor (EGFR). The activation of EGFR-associated signaling pathways leads to a decreased expression of integrin, increased β-catenin phosphorylation, and E-...