Hexokinase (ATP: D-hexose 6-phosphotransferase, EC 2.7.1.1; HK) deficiency is a rare disease where the predominant clinical effect is nonspherocytic hemolytic anemia. We have previously shown that the only patient for which hexokinase deficiency has been so far investigated at molecular level is...
Hexokinase (Hex) locus structure in Tribolium and Hex gene evolution in insects.Amanda, Fraga
Structure of the human hexokinase II gene. Malkki,M,Laakso,M,Deeb,SS. Biochemical and Biophysical Research Communications . 1994Malkki, M., Laakso, M., and Deeb, S.S. (1994). Structure of the human hexokinase II gene. Biochem Biophys Res Commun 205, 490-496....
Hexokinase as a sugar sensor in higher plants. Hexokinase 2 is a key mediator of aerobic glycolysis and promotes tumor growth in human glioblastoma multiforme Isozymes of mammalian hexokinase: structure, subcellular localization and metabolic function ...
Mouse hexokinase II gene: structure, cDNA, promoter analysis, and expression pattern. Mamm Genome 2000; 11: 91–96. Article CAS PubMed Google Scholar Mayer SE, Mayfield AC, Haas JA . Heart muscle hexokinase: subcellular distribution and inhibition by glucose 6-phosphate. Mol Pharmacol 1966; ...
The 3D structure of VDAC1 reveals that it consists of a β-barrel consisting of 19 transmembrane β-chains connected by flexible loops and a 25-residue-long N-terminal domain containing anα helixwithin the pore (Hiller et al., 2010). This region could regulate the transport of substances ...
E. Isozymes of mammalian hexokinase: structure, subcellular localization and metabolic function. J. Exp. Biol. 206, 2049–2057 (2003). Article PubMed CAS Google Scholar Guo, C. et al. Coordinated regulatory variation associated with gestational hyperglycaemia regulates expression of the novel ...
Its basic structure consists of a hexose sugar molecule attached to a phosphate group. This enzyme is soluble in water. HEXOKINASE is generally considered safe, but it is important to handle it with caution and follow proper laboratory safety protocols when working with enzymes. It is recommended...
References 1. Aleshin, A.E. et al. (1998) Structure 6:39-50 2. Takeda, J. et al. (1993) J. Biol. Chem. 268:15200. 3. Lange, A.J. et al. (1991) Biochem. J. 277:159–163. 4. Magnani, M. et al., J. Biol. Chem. 266: 502. ...
HEXOKINASE structure CAS No. 9001-51-8 Chemical Name: HEXOKINASE Synonyms HK;HK III;C:C&B14;EC 2.7.1.1;HEXOKINASE;EC: 2.7.1.1;IUB: 2.7.1.1;Hexokinase 1;Hexokinase D;Hexokinase IV CBNumber: CB5394638 Molecular Formula: N/A Molecular Weight: 0 MDL Number: MFCD00131321 MOL File: ...