建议收到该Hexokinase Domain Containing 1 (HKDC1) Antibody产品后,储存温度为-20°C。避免重复冻融其他 Abbexa总部位于英国剑桥的剑桥科学园,是一家专业的全球抗体供应商和蛋白质供应商,致力于为生命科学、药物开发和生物技术领域的科学家和研究者提供最佳的客户体验和高质量的产品。产品涵盖一抗、二抗、蛋白质、ELI...
Hexokinase domain containing 1 (HKDC1) gene was discovered as a gene related to glucose metabolism during pregnancy compared with nongravid state.HKDC1plays a critical role in glucose homeostasis during pregnancy. Haplotypes ofHKDC1genetic variants associated with 2-h plasma glucose (2hPG) in ...
Hexokinase Domain Containing 1 (HKDC1) Gene Variants and their Association with Gestational Diabetes Mellitus in a South Indian Population Summary Hexokinase domain containing 1 ( HKDC1 ), a novel human hexokinase gene, is known to affect glucose metabolism and was shown to have a strong assoc.....
Hexokinase domain containing 1, a recently discovered putative fifth hexokinase, is hypothesized to play key roles in glucose metabolism. Specifically, during pregnancy in a recent genome wide association study (GWAS), a strong correlation between HKDC1 and 2-h plasma glucose in pregnant women from...
(a) Known genes: Hexokinase domain containing 1 (HKDC1) , Hexokinase 1 (HK1) and FLJ31406. (b) Alternative exons supported by mRNAs and ESTs. (c) Positions of SNPs and insertion/deletions: grey – previously published;11 black – identified in this study; and boxed – variants not ...
The 3D structure of VDAC1 reveals that it consists of a β-barrel consisting of 19 transmembrane β-chains connected by flexible loops and a 25-residue-long N-terminal domain containing anα helixwithin the pore (Hiller et al., 2010). This region could regulate the transport of substances ...
We also establish that GCK evolved from a two hexokinase domain-containing gene, but has lost its N-terminal hexokinase domain. We also show that parallel changes in enzymatic function of HKI and HKIII have occurred. 展开 关键词: Glucokinase Gene duplication Hexokinase Gene evolution ...
HK domain containing 1 IBD: Inflammatory bowel disease IEC: Intestinal epithelial cell IL: Interleukin ITGA2B: Integrin alpha 2b ITGAM: Integrin alpha M NOD2: Nucleotide-binding oligomerization domain-containing protein 2 OXPHOS: Oxidative phosphorylation PBS: Phosphate-buffered saline PPIF...
saline containing 0.1% Tween-20 [TBS-T]), the wells were incubated in serum (1:1000 diluted in 3% BSA in TBS-T) for 2 hours, followed by horseradish peroxidase (HRP)-labeled anti-human IgG secondary antibodies (1:5000) for 1 hour, to quantify total levels of anti-hexokinase 1 ...
While there are several varieties of inflammasomes, the one responsible for responding to PGN is defined by the presence of NOD-like receptor family, pyrin domain-containing 3 (NLRP3). The mechanism by which NLRP3 is activated by PGN is not known. It is generally thought that all of the ...