Fibrin clot properties in wom‑ en heterozygous for factor V Leiden mutation: effects of oral contraceptives. Thromb Res. 2012; 130: e216‑e221.Krzek M, Ciesla-Dul M, Zabczyk M, et al. Fibrin clot properties in women het- erozygous for factor V Leiden mutation: effects of oral...
The risk of first venous thromboembolism during pregnancy and puerperium in double heterozygotes for factor V Leiden and prothrombin G20210A Background : The risk of venous thromboembolism (VTE) during pregnancy in double heterozygous carriers of factor (F) V Leiden and prothrombin G20210A is no....
Activated protein C resistance, caused by a point mutation factor V gene was described in last decade. This article highlights a case of a 9 year-old-boy who admitted to Ba艧kent University Hospital with right- sided hemiplegia. He was diagnosed as heterozygous for the FVL muta- tion and ...
Genetic study revealed factor V Leiden mutation and homozygous mutation G20210A in prothrombin gene. CONCLUSIONS: Both mutations found in this case, alone, are not a high risk factors for venous thrombosis but together may increase 5-10 fold risk of venous thrombosis. Venous stroke must be ...
Genetic analysis revealed that he was heterozygous for the prothrombin Factor V (FV) Leiden and MTHFR C677T mutations. Therapy started with intravenous heparin, followed by warfarin. He had no other episodes over a 2-year follow-up. Lifelong oral anticoagulant therapy was recommended. 展开 ...
It is well documented that factor V Leiden mutation (FVL) is a common hypercoagulable risk factor in the Caucasian population. Patients with homozygous FVL mutation have an increased risk for venous thromboembolism. However, there have been few cases of heterozygous FVL mutation associated with ...
Previous studies suggest that risk of premature myocardial infarction is increased by a heritable factor not associated with the conventional risk factors. Among the 5–7% of persons in the general population at high risk, the men are at greater risk than the women. It is proposed that heterozyg...
Heterozygous PINK1 mutations: A susceptibility factor for Parkinson disease? PINK1 mutations cause recessively inherited early-onset Parkinson's disease (EOPD). We comprehensively tested 75 Serbian and 17 South Tyrolean EOPD patient... A Djarmati,K Hedrich,M Svetel,... - 《Movement Disorders》 ...
Congenital resistance to activated protein C due to a point mutation in the factor V gene (Gln506-FV) is the most common genetic risk factor for familial venous thrombosis. Considering the central role of activated protein C as a physiological anticoagulant, the question of why the thrombotic ri...
caused by heterozygous nonsense mutations of FGG, Shizuoka III and Kanazawa II.###Dusart Syndrome in a Scandinavian family characterized by arterial and venous thrombosis at young age.###Inhibition of thrombin-mediated factor V activation contributes to the anticoagulant activity of fibrinogen '. 来...