Fibrin clot properties in wom‑ en heterozygous for factor V Leiden mutation: effects of oral contraceptives. Thromb Res. 2012; 130: e216‑e221.Krzek M, Ciesla-Dul M, Zabczyk M, et al. Fibrin clot properties in women het- erozygous for factor V Leiden mutation: effects of oral...
Activated protein C resistance, caused by a point mutation factor V gene was described in last decade. This article highlights a case of a 9 year-old-boy who admitted to Ba艧kent University Hospital with right- sided hemiplegia. He was diagnosed as heterozygous for the FVL muta- tion and ...
Having different alleles at a given locus on the pair of chromosomes present in the diploid state; for example, having a normal beta globin gene (coding for normal hemoglobin, Hb A) at locus p15.5 on one chromosome 11 and an abnormal gene (coding for sickle-cell hemoglobin, Hb S) at th...
It is well documented that factor V Leiden mutation (FVL) is a common hypercoagulable risk factor in the Caucasian population. Patients with homozygous FVL mutation have an increased risk for venous thromboembolism. However, there have been few cases of heterozygous FVL mutation associated with ...
Combined oral contraceptives and factor V Leiden mutation are multiplicative risk factors for venous thromboembolism. However, it remains unknown whether this multiplicative effect is reflected in thrombin generation assays. We report here the evolution of the thrombin generation profile while taking ...
The relationship of the factor V Leiden mutation and pregnancy outcomes for mother and fetus. OBJECTIVE: We sought to estimate the frequency of pregnancy-related thromboembolic events among carriers of the factor V Leiden (FVL) mutation without a pe... D Dizon-Townson,C Miller,B Sibai,... ...
Objective: The factor V Leiden (FVL) mutation (Arg506Glu) results in the production of a FV protein that when activated, is relatively resistant to inactiv... S Schoenmakers,A Groot 被引量: 0发表: 2008年 加载更多来源期刊 Journal of Thrombosis & Haemostasis Jth 2015/7/19 12:37:00 研究...
Budd-Chiari syndromefactor V Leiden mutationhepatic outflowobstructionprothrombin gene mutationrisk factors for thrombosisA young female, who had been in ... W Petry,O Adams,D Häussinger - 《Journal of Hepatology》 被引量: 34发表: 2000年 Idiopathic Budd–Chiari syndrome in a patient with homo...
Genetic analysis revealed that he was heterozygous for the prothrombin Factor V (FV) Leiden and MTHFR C677T mutations. Therapy started with intravenous heparin, followed by warfarin. He had no other episodes over a 2-year follow-up. Lifelong oral anticoagulant therapy was recommended. 展开 ...
OV Fofanova-Gambetti,V Hwa,S Kirsch,... - 《Hormone Research》 被引量: 107发表: 2009年 Identification of a Novel Heterozygous IGF1 Splicing Mutation in a Large Kindred with Familial Short Stature Background/Aims: Insulin-like growth factor (IGF)-I is critical for normal human growth. Extre...