Herpes Simplex Virus Type 2 Suppressive Therapy with Acyclovir or Valacyclovir Does Not Select for Specific HIV-1 Resistance in HIV-1/HSV-2 Dually Infected PersonsRecent in vitro studies suggest that acyclovir may directly inhibit HIV-1 replication and can select for a specific HIV-1 reverse ...
HSV-2, suppressive therapy, inflammation, HIV-1/HSV-2 co-infectionBackgroundHerpes simplex virus type-2 (HSV-2) may heighten immune activation and increase HIV-1 replication, resulting in greater infectivity and faster HIV-1 disease progression. An 18-week randomized, placebo-controlled crossover...
Empiric Therapy Regimens Although lesions caused by herpes simplex virus (HSV) subtypes HSV-1 and HSV-2 differ in rates of recurrence and subclinical shedding, they are treated with the same antiviral regimens, based on the site of infection. [1, 2, 3, 4] Genital herpes First episode ...
Humans are blessed with at least five herpesviruses, i.e., herpes simplex 1 (human herpesvirus 1, HSV-1), herpes simplex 2 (human herpesvirus 2, HSV-2), herpes zoster virus (human herpesvirus 3, HZV), Epstein-Barr virus (human herpesvirus 4, EBV), cytome
HSV suppression reduces seminal HIV-1 levels in HIV-1/HSV-2 co-infected men who have sex with men Objectives:Suppressive herpes simplex virus (HSV) therapy can decrease plasma, cervical, and rectal HIV-1 levels in HIV-1/HSV-2 co-infected persons. We eva... RA Zuckerman,A Lucchetti,WLH...
Correlation between response to acyclovir and foscarnet therapy and in vitro susceptibility result for isolates of herpes simplex virus from human immunode... to acyclovir and foscarnet therapy and in vitro susceptibility result for isolates of herpes simplex virus from human immunodeficiency virus-infecte...
Oncolytic virus therapy of multiple tumors in the brain requires suppression of innate and elicited antiviral responses. Nat Med 1999; 5: 881–887. Article CAS PubMed Google Scholar Morahan PS, Thomson TA, Kohl S, Murray BK . Immune responses to labial infection of BALB/c mice with herpes...
Suppression of the immune system (for example, by a medication taken to prevent rejection of an organ transplant) Physical trauma, such as a dental procedure Overexposure of the lips to sunlight Often, the trigger is unknown. Symptoms and Complications of HSV Infections Tiny blisters appear on th...
The purpose of this review is to summarize available experimental and clinical data concerning benefits and potential risks of photodynamic therapy for oral and genital herpes simplex virus infections. Since such infections are a source of discomfort and pain, and since recent evidence links the virus...
Herpes simplex virus (HSV) has become one of the most widely clinically used oncolytic agent. Various types of HSV have been studied in basic or clinical research. Combining oncolytic virotherapy with chemotherapy or radiotherapy generally produces synergic action with unclear molecular mechanisms. ...